Evidence map›Paper›PMID 30622132›Full record

ArticleThe Journal of general physiology2019

Reinterpretation of the substrate specificity of the voltage-sensing phosphatase during dimerization.

Martin Kruse, Susy C Kohout, Bertil Hille

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of general physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. With PIPs, you get ZIPs and blips.The Journal of general physiology · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Martin KruseDepartment of Biology and Program in Neuroscience, Bates College, Lewiston, ME.ORCID 0000-0003-4301-8385
Susy C KohoutDepartment of Cell Biology and Neuroscience, Montana State University, Bozeman, MT.ORCID 0000-0002-8159-8934
Bertil HilleDepartment of Physiology and Biophysics, University of Washington School of Medicine, Seattle, WA hille@uw.edu.ORCID 0000-0002-7266-1671
Bates College · USMontana State University · USUniversity of Washington · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
TR&D4 Spatial Modeling: Modeling Framework for Cell MotilityP41GM103313 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LOEW, LESLIE M · 2012 to 2018
$9.7M
Molecular Properties of Ionic Permeability in NerveR37NS008174 · NINDS · UNIVERSITY OF WASHINGTON · PI HILLE, BERTIL · 2013 to 2019
$3.8M
Molecular mechanisms behind the voltage sensing phosphatase signalingR01GM111685 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI KOHOUT, SUSY C · 2015 to 2018
$1.1M
NIGMS NIH HHS P20 GM103423NIGMS NIH HHS P41 GM103313NIGMS NIH HHS R01 GM111685NINDS NIH HHS R37 NS008174
6 · The paper itself

Abstract

Voltage-sensing phosphatases (VSPs) cleave both 3- and 5-phosphates from inositol phospholipids in response to membrane depolarization. When low concentrations of

Indexed as

Protein MultimerizationAnimalsHumansMembrane PotentialsPhosphoric Monoester HydrolasesSubstrate SpecificityXenopusPhosphoric Monoester Hydrolasesvoltage-sensor-containing phosphatase, Ciona intestinalis

Identifiers

PMID30622132
PMCPMC6363406
OpenAlexW2911126600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.