Evidence map›Paper›PMID 30622089›Full record

ArticleJMIR research protocols2019

Treatment of Atopic Dermatitis Using a Full-Body Blue Light Device (AD-Blue): Protocol of a Randomized Controlled Trial.

Christian Kromer, Viktoria P Nühnen, Wolfgang Pfützner, Sebastian Pfeiffer, Hans-Joachim Laubach, Wolf-Henning Boehncke, Joerg Liebmann, Matthias Born, Michael P Schön, Timo Buhl

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03085303 (Treatment of Atopic Dermatitis by a Full-Body Blue Light Device), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03085303 nacompletednot on this map

Treatment of Atopic Dermatitis by a Full-Body Blue Light Device

TypeinterventionalSponsorPhilips Electronics Nederland BVRan2017 to 2018Enrolled87ConditionsDermatitis, AtopicArmsFull Body Blue Light Device
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Phototherapy for atopic eczema.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Christian KromerDepartment of Dermatology, Venereology, and Allergology, University Medical Centre Göttingen, Göttingen, Germany.ORCID http://orcid.org/0000-0003-2197-4907
Viktoria P NühnenDepartment of Dermatology, Venereology, and Allergology, University Medical Centre Göttingen, Göttingen, Germany.ORCID http://orcid.org/0000-0002-6234-2298
Wolfgang PfütznerClinic for Dermatology and Allergology, University of Marburg, Marburg, Germany.ORCID http://orcid.org/0000-0002-8721-724X
Sebastian PfeifferClinical Trials Unit, University Medical Centre Göttingen, Göttingen, Germany.ORCID http://orcid.org/0000-0002-4458-0292
Hans-Joachim LaubachDivision of Dermatology and Venereology, Geneva University Hospital, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-6831-6517
Wolf-Henning BoehnckeDivision of Dermatology and Venereology, Geneva University Hospital, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-1225-7124
Joerg LiebmannPhilips GmbH, Innovative Technologies, Aachen, Germany.ORCID http://orcid.org/0000-0001-9280-2614
Matthias BornPhilips GmbH, Innovative Technologies, Aachen, Germany.ORCID http://orcid.org/0000-0002-7710-6511
Michael P Schön *Department of Dermatology, Venereology, and Allergology, University Medical Centre Göttingen, Göttingen, Germany.ORCID http://orcid.org/0000-0002-0698-4130
Timo Buhl *Department of Dermatology, Venereology, and Allergology, University Medical Centre Göttingen, Göttingen, Germany.ORCID http://orcid.org/0000-0002-3139-129X
Philips (Germany) · DEPhilipps University of Marburg · DEUniversity Hospital of Geneva · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIrradiation with visible blue light (wavelength 400-495 nm) is a promising, effective, and safe new treatment option for chronic inflammatory skin diseases such as psoriasis and atopic dermatitis.

objectiveWe will perform a multicenter, placebo-controlled, double-blinded, 3-armed, prospective, randomized controlled trial to investigate the efficacy and safety of full-body blue light devices (wavelengths: 415 nm and 450 nm) compared with that of placebo irradiation for the treatment of atopic dermatitis.

methodsWe are planning to enroll a total of 150 patients at the University hospitals in Göttingen (Germany), Marburg (Germany), and Geneva (Switzerland).

resultsThe trial was approved by the lead ethics committee of the medical faculty of the University of Göttingen (21/11/16). Further approvals were obtained from local and federal authorities (ethics committee Marburg, Cantonal Commission for Research Ethics Geneva, Suisse Medic, and Bundesinstitut für Arzneimittel und Medizinprodukte).

conclusionsWe will disseminate the results in a peer-reviewed journal.

trial registrationClinicalTrials.gov NCT03085303; https://clinicaltrials.gov/ct2/show/NCT03085303 (Archived by WebCite at http://www.webcitation.org/73ucqkkA1). INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/11911.

Indexed as

atopic dermatitisatopic eczemablue lightirradiationultraviolet light

Identifiers

PMID30622089
PMCPMC6329412
OpenAlexW2911029768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.