Evidence map›Paper›PMID 30622071›Full record

ArticleEnvironment international2019

Maternal swimming pool exposure during pregnancy in relation to birth outcomes and cord blood DNA methylation among private well users.

Lucas A Salas, Emily R Baker, Mark J Nieuwenhuijsen, Carmen J Marsit, Brock C Christensen, Margaret R Karagas

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Exposure to Chloramine and Chloroform in Tap Water and Adverse Perinatal Outcomes in Shanghai.International journal of environmental research and public health · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lucas A SalasDepartment of Epidemiology, The Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon 03756, NH, USA; The Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Lebanon 03756, NH, USA. Electronic address: Lucas.A.Salas.Diaz@Dartmouth.Edu.
Emily R BakerDepartment of Obstetrics and Gynecology, The Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon 03756, NH, USA. Electronic address: emily.r.baker@dartmouth.edu.
Mark J NieuwenhuijsenISGlobal, The Barcelona Institute for Global Health, Barcelona 08003, Catalonia, Spain; Universitat Pompeu Fabra (UPF), Barcelona 08003, Catalonia, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona 08003, Catalonia, Spain. Electronic address: mark.nieuwenhuijsen@isglobal.org.
Carmen J MarsitDepartment of Environmental Health, Rollins School of Public Health of Emory University, Atlanta 30322, GA, USA. Electronic address: carmen.j.marsit@emory.edu.
Brock C ChristensenDepartment of Epidemiology, The Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon 03756, NH, USA; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon 03756, NH, USA; Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon 03756, NH, USA. Electronic address: brock.c.christensen@dartmouth.edu.
Margaret R KaragasDepartment of Epidemiology, The Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon 03756, NH, USA; The Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Lebanon 03756, NH, USA. Electronic address: margaret.r.karagas@dartmouth.edu.
Dartmouth College · USBarcelona Institute for Global Health · ESEmory University · US

Funding

Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2013 to 2022
$23.7M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Project 3: Placental Biomarkers of Exposure and Outcome (Marsit)P01ES022832 · NIEHS · DARTMOUTH COLLEGE · PI MURRAY, CAROLYN J · 2013 to 2018
$4.7M
Training Program for Quantitative Population Sciences in CancerR25CA134286 · NCI · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA, TOSTESON, TOR D · 2009 to 2018
$3.0M
Enriching the Rhode Island Child Health StudyR24ES028507 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit, LAURA R STROUD · 2017 to 2026
$2.3M
Project 4: Determining How Arsenic Modulates Hedgehog Signaling During DevelopmenP20ES018175 · NIEHS · DARTMOUTH COLLEGE · PI ROBBINS, DAVID J · 2010 to 2012
$892k
Environmental influences and function of cytosine modification in human placentaR21ES028226 · NIEHS · EMORY UNIVERSITY · PI MARSIT, CARMEN JOSEPH · 2017 to 2018
$429k
NCI NIH HHS R25 CA134286NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P20 ES018175NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R21 ES028226NIEHS NIH HHS R24 ES028507NIGMS NIH HHS P20 GM104416
6 · The paper itself

Abstract

Swimming in pools during pregnancy may expose the fetus to water disinfection by-products (DBP). As yet, our understanding of the impacts on DBPs on the fetus is uncertain. Individuals with public water systems are typically exposed to DBPs through drinking, showering and bathing, whereas among those on private water systems, swimming in pools may be the primary exposure source. We analyzed the effects of maternal swimming on birth outcomes and cord blood epigenetic changes in the New Hampshire Birth Cohort Study, a cohort of pregnant women with households on private water systems. Information about swimming in pools during pregnancy was obtained from 1033 women via questionnaires. Swimming pool use and duration were modeled using linear regression with newborn weight, length, and head circumference (z-scores) and genome wide cord blood DNA methylation as the outcomes and with adjustment for potential confounders. Overall 19.7% of women reported swimming in a pool during pregnancy. Among swimmers, duration of swimming was inversely related to head circumference (-0.02 z-score per 10% increase in duration, P = 0.004). No associations were observed with birth weight, length or DNA methylation modifications. Our findings suggest swimming pool exposure may impact the developing fetus although longer-term studies are needed.

Indexed as

DNA MethylationInfant, NewbornSwimming PoolsAdultBirth WeightCohort StudiesDisinfectionFemaleFetal BloodHumansMaleMaternal ExposurePregnancySwimmingWater Wells

Identifiers

PMID30622071
PMCPMC6599635
OpenAlexW2908056341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.