Evidence map›Paper›PMID 30621634›Full record

ArticleBMC nephrology2019

Longitudinal patterns of health-related quality of life and dialysis modality: a national cohort study.

Nwamaka D Eneanya, Dugan W Maddux, Marta M Reviriego-Mendoza, John W Larkin, Len A Usvyat, Frank M van der Sande, Jeroen P Kooman, Franklin W Maddux

Registry-linked trialAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06274710 (Open Access Digital CommunitY Promoting Self-Care, Peer Support, and HEalth LitEracy), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06274710 narecruitingnot on this mapstarted 2023, after this paper: background citation

Open Access Digital CommunitY Promoting Self-Care, Peer Support, and HEalth LitEracy (ODYSSEE) for Kidney Health (KH) Trial

TypeinterventionalSponsorUniversity Health Network, TorontoRan2023 to 2026Enrolled344ConditionsChronic Kidney DiseasesArmsODYSSEE-KH
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Home versus in-centre haemodialysis for people with kidney failure.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Observational
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  7. Review
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  11. Review
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  16. Observational
  17. The current and future landscape of dialysis.Nature reviews. Nephrology · 2020
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nwamaka D EneanyaRenal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 307 Blockley Hall, 423 Guardian Drive, Philadelphia, PA, 19104, USA. Nwamaka.Eneanya@pennmedicine.upenn.edu.ORCID 0000-0002-0508-3410
Dugan W MadduxFresenius Medical Care North America, Waltham, MA, USA.
Marta M Reviriego-MendozaFresenius Medical Care North America, Waltham, MA, USA.
John W LarkinFresenius Medical Care North America, Waltham, MA, USA.
Len A UsvyatFresenius Medical Care North America, Waltham, MA, USA.
Frank M van der SandeDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, Netherlands.
Jeroen P KoomanDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, Netherlands.
Franklin W MadduxFresenius Medical Care North America, Waltham, MA, USA.

Funding

Integrating Conservative Kidney Management Options and Advance Care Planning Into a Pre-Dialysis Educational ProgramK23DK114526 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ENEANYA, NWAMAKA · 2017 to 2021
$819k
NIDDK NIH HHS K23 DK114526
6 · The paper itself

Abstract

backgroundHealth-related quality of life (HrQoL) varies among dialysis patients. However, little is known about the association of dialysis modality with HrQoL over time. We describe longitudinal patterns of HrQoL among chronic dialysis patients by treatment modality.

methodsNational retrospective cohort study of adult patients who initiated in-center dialysis or a home modality (peritoneal or home hemodialysis) between 1/2013 and 6/2015. Patients remained on the same modality for the first 120 days of the first two years. HrQoL was assessed by the Kidney Disease and Quality of Life-36 (KDQOL) survey in the first 120 days of the first two years after dialysis initiation. Home modality patients were matched to in-center patients in a 1:5 fashion.

resultsIn-center (n=4234) and home modality (n=880) patients had similar demographic and clinical characteristics. In-center dialysis patients had lower mean KDQOL scores across several domains compared to home modality patients. For patients who remained on the same modality, there was no change in HrQoL. However, there were trends towards clinically meaningful changes in several aspects of HrQoL for patients who switched modalities. Specifically, physical functioning decreased for patients who switched from home to in-center dialysis (p< 0.05).

conclusionsAmong a national cohort of chronic dialysis patients, there was a trend towards different patterns of HrQoL life that were only observed among patients who changed modality. Patients who switched from home to in-center modalities had significant lower physical functioning over time. Providers and patients should be mindful of HrQoL changes that may occur with dialysis modality change.

Indexed as

Quality of LifeAdultAgedFemaleHemodialysis, HomeHemodialysis Units, HospitalHumansLongitudinal StudiesMaleMiddle AgedOutpatientsRenal DialysisRetrospective StudiesSurveys and QuestionnairesUnited StatesDialysisdialysis modalityquality-of-life

Identifiers

PMID30621634
PMCPMC6325821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.