Evidence map›Paper›PMID 30621610›Full record

ArticleBMC infectious diseases2019

Helicobacter pylori infection among patients presenting with dyspepsia at a primary care setting in Cameroon: seroprevalence, five-year trend and predictors.

Jeannine A Aminde, Guisilla A Dedino, Calypse A Ngwasiri, Kingsley S Ombaku, Cedric A Mahop Makon, Leopold Ndemnge Aminde

Abstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Association betweenFrontiers in medicine · 2025
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  9. Evaluation of Anti-Diagnostics (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Seroprevalence ofAccess microbiology · 2022
    Article
  12. Prevalence ofJournal of tropical medicine · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeannine A AmindeFaculty of Health Sciences, University of Buea, Buea, Cameroon. jeannineatemanyingu@rocketmail.com.ORCID http://orcid.org/0000-0003-3149-6494
Guisilla A DedinoRegina Pacis Hospital, Mutengene, Cameroon.
Calypse A NgwasiriClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.
Kingsley S OmbakuWum District Hospital, Wum, Cameroon.
Cedric A Mahop MakonWum District Hospital, Wum, Cameroon.
Leopold Ndemnge AmindeClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlmost half the world's population is infected with Helicobacter pylori (H. pylori) with the highest reported prevalence from Africa. This infection is associated with several morbid gastrointestinal conditions. Understanding the trends in seroprevalence and the factors associated with H. pylori seropositivity in dyspeptic persons can provide a guide for public health policies.

methodsThis was a retrospective study, carried out with outpatient records of Wum District Hospital (WDH) from January 2012 to December 2016. We reviewed records of all patients for whom a H. pylori serology test was requested. The Cochran-Armitage trend test and multiple regression models were used to explore seroprevalence trends and predictors of seropositivity respectively.

resultsWe included 451 records, 63.6% (n = 287) were female. The mean age of the study population was 40.7 years, and the overall H. pylori seroprevalence was 51.5% (95% CI: 47-56%). The use of recommended eradication regimen appears to be low and declining. On average, H. pylori seroprevalence declined by 6.8% annually (p < 0.0001). Occupational status independently predicted seropositivity, with students having lower odds of being seropositive than employed persons (aOR = 0.09, 95% CI: 0.02-0.49, p = 0.016).

conclusionDespite decreasing trends, the seroprevalence of Helicobacter pylori infection is high in dyspeptic patients attending this primary care setting. Improving living standards and establishing national guidelines for eradication can possibly aid the control of this infection.

Indexed as

Helicobacter pyloriAdolescentAdultAgedAged, 80 and overAntibodies, BacterialCameroonChildDyspepsiaFemaleHelicobacter InfectionsHumansMaleMiddle AgedPrevalencePrimary Health CareAntibodies, BacterialCameroonHelicobacter pyloriPrimary careSeroprevalenceTrends

Identifiers

PMID30621610
PMCPMC6325826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.