Evidence map›Paper›PMID 30621360›Full record

ArticleMolecules (Basel, Switzerland)2019

Thiophene Derivatives as Anticancer Agents and Their Delivery to Tumor Cells Using Albumin Nanoparticles.

Guangsheng Cai, Simiao Wang, Lang Zhao, Yating Sun, Dongsheng Yang, Robert J Lee, Menghui Zhao, Huan Zhang, Yulin Zhou

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Thiophene-based water-soluble CBiomaterials translational · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Cyclotrisiloxan and β-Sitosterol richSaudi journal of biological sciences · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Guangsheng CaiCollege of Life Sciences, Jilin University, Changchun 130012, China. caigs15@mails.jlu.edu.cn.
Simiao WangCollege of Life Sciences, Jilin University, Changchun 130012, China. wangsm1317@mails.jlu.edu.cn.
Lang ZhaoCollege of Chemistry, Jilin University, Changchun 130012, China. zlang2009@163.com.
Yating SunCollege of Life Sciences, Jilin University, Changchun 130012, China. 18744026372@sina.cn.
Dongsheng YangSchool of Pharmaceutical and Food Sciences, Zhuhai College of Jilin University, Zhuhai 519041, China. 07034@jluzh.com.
Robert J LeeCollege of Life Sciences, Jilin University, Changchun 130012, China. lee.1339@osu.edu.ORCID 0000-0002-5981-5867
Menghui ZhaoCollege of Life Sciences, Jilin University, Changchun 130012, China. zhaomh18@mails.jlu.edu.cn.
Huan ZhangCollege of Life Sciences, Jilin University, Changchun 130012, China. zhang_huan1020@163.com.
Yulin ZhouCollege of Life Sciences, Jilin University, Changchun 130012, China. zhouyl133@jlu.edu.cn.
Jilin University · CN

Funding

Key Platform and Major Research Program of Guangdong Provincial University 2017GXJK221National Natural Science Foundation of China 21772063National Natural Science Foundation of China 81502999
6 · The paper itself

Abstract

A series of thiophene derivatives (TPs) were synthesized and evaluated for cytotoxicity in HepG2 and SMMC-7721 cell lines by MTT assay. TP

Indexed as

AlbuminsAntineoplastic AgentsBiological TransportCell Line, TumorCell SurvivalDelayed-Action PreparationsDrug CarriersDrug DesignDrug LiberationHumansMolecular StructureNanoparticlesParticle SizeReactive Oxygen SpeciesSolubilityStructure-Activity RelationshipAlbuminsAntineoplastic AgentsDelayed-Action PreparationsDrug CarriersReactive Oxygen SpeciesThiophenescytotoxicitydrug deliveryhuman serum albuminnanoparticlesthiophene derivatives

Identifiers

PMID30621360
PMCPMC6337126
OpenAlexW2907916602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.