Evidence map›Paper›PMID 30621329›Full record

ArticleMaterials (Basel, Switzerland)2019

Sol⁻Gel Synthesis of Silica-Based Materials with Different Percentages of PEG or PCL and High Chlorogenic Acid Content.

Elisabetta Tranquillo, Federico Barrino, Giovanni Dal Poggetto, Ignazio Blanco

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Silica Aerogel-Polycaprolactone Scaffolds for Bone Tissue Engineering.International journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elisabetta TranquilloDepartment of Engineering, University of Campania "Luigi Vanvitelli", via Roma 29, 81031 Aversa, Italy. elisabetta.tranquillo@unicampania.it.
Federico BarrinoDepartment of Engineering, University of Campania "Luigi Vanvitelli", via Roma 29, 81031 Aversa, Italy. federicobarrino92@hotmail.it.
Giovanni Dal PoggettoEcoricerche srl, via Principi Normanni 36, 81043 Capua Caserta, Italy. giogiodp@hotmail.it.
Ignazio BlancoDepartment of Civil Engineering and Architecture and UdR-Catania Consorzio INSTM, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy. iblanco@unict.it.ORCID 0000-0001-9252-9435
University of Campania "Luigi Vanvitelli" · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implanted biomedical devices can induce adverse responses in the human body, which can cause failure of the implant-referred to as implant failure. Early implant failure is induced numerous factors, most importantly, infection and inflammation. Natural products are, today, one of the main sources of new drug molecules due to the development of pathogenic bacterial strains that possess resistance to more antibiotics used currently in various diseases. The aim of this work is the sol⁻gel synthesis of antibacterial biomedical implants. In the silica matrix, different percentages (6, 12, 24, 50 wt %) of polyethylene glycol (PEG) or poly(ε-caprolactone) (PCL) were embedded. Subsequently, the ethanol solutions with high amounts of chlorogenic acid (CGA 20 wt %) were slowly added to SiO₂/PEG and SiO₂/PCL sol. The interactions among different organic and inorganic phases in the hybrid materials was studied by Fourier transform infrared (FTIR) spectroscopy. Furthermore, the materials were soaked in simulated body fluid (SBF) for 21 days and the formation of a hydroxyapatite layer on their surface was evaluated by FTIR and XRD analysis. Finally,

Indexed as

antibacterial activitybiomaterialschlorogenic acidhybrid materialsPCLPEGsol–gel method

Identifiers

PMID30621329
PMCPMC6337738
OpenAlexW2906849631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.