Evidence map›Paper›PMID 30621263›Full record

ArticleNutrients2019

Maternal High-Protein Diet during Pregnancy Modifies Rat Offspring Body Weight and Insulin Signalling but Not Macronutrient Preference in Adulthood.

Gabrielle Carlin, Catherine Chaumontet, François Blachier, Pierre Barbillon, Nicolas Darcel, Anne Blais, Corine Delteil, Florence M Guillin, Sophie Blat, Eline M van der Beek and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Protein, amino acids and obesity treatment.Reviews in endocrine & metabolic disorders · 2020
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Gabrielle CarlinUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. gabrielle.carlin@agroparistech.fr.
Catherine ChaumontetUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. catherine.chaumontet@agroparistech.fr.
François BlachierUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. francois.blachier@agroparistech.fr.
Pierre BarbillonUMR MIA-Paris, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. pierre.barbillon@agroparistech.fr.ORCID 0000-0002-7766-7693
Nicolas DarcelUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. nicolas.darcel@agroparistech.fr.
Anne BlaisUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. anne.blais@agroparistech.fr.
Corine DelteilUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. corine.delteil@agroparistech.fr.
Florence M GuillinUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. florence.guillin@agroparistech.fr.
Sophie BlatINRA, INSERM, Univ Rennes, Nutrition Metabolisms and Cancer, NuMeCan, 35000 Rennes, France. sophie.blat@inra.fr.
Eline M van der BeekDanone Nutricia Research, 3584 CT Utrecht, The Netherlands. eline.vanderbeek@danone.com.
Andrea KoddeDanone Nutricia Research, 3584 CT Utrecht, The Netherlands. andrea.kodde@danone.com.
Daniel ToméUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. daniel.tome@agroparistech.fr.
Anne-Marie DavilaUMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France. davila@agroparistech.fr.ORCID 0000-0003-4469-5628
AgroParisTech · FRDanone (Netherlands) · NLInserm · FRUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diet of mothers during gestation may impact offspring phenotype. This study evaluated the consequences of a maternal High-Protein (HP) diet during gestation on food preferences and phenotypic characteristics in adult rat offspring. Dams were fed a HP or a Normal-Protein (NP) isocaloric diet during gestation only. Weaned female pups were divided into 3 diet groups: NP control or one of two dietary self-selection (DSS) conditions. In DSS1, offspring had a free choice between proteins (100%) or a mix of carbohydrates (88%) and lipids (12%). In DSS2, the choice was between proteins (100%), carbohydrate (100%) or lipids (100%). DSS2 groups consumed more of their energy from protein and lipids, with a decreased carbohydrate intake (

Indexed as

Body WeightDiet, High-ProteinPrenatal Exposure Delayed EffectsAdiposityAnimalsBody CompositionDietary CarbohydratesDietary FatsDietary ProteinsEnergy IntakeFemaleFood PreferencesInsulinLeptinLiverMaternal Nutritional Physiological PhenomenaDietary CarbohydratesDietary FatsDietary ProteinsInsulinLeptinNutrientsadipositydietary self-selectionfood preferencesgestationhigh-protein dietprogrammingrat

Identifiers

PMID30621263
PMCPMC6356951
OpenAlexW2906797007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.