Evidence map›Paper›PMID 30621163›Full record

ArticleInternational journal of molecular sciences2019

Inhibition of Breast Cancer Cell Invasion by Ras Suppressor-1 (RSU-1) Silencing Is Reversed by Growth Differentiation Factor-15 (GDF-15).

Vasiliki Gkretsi, Maria Louca, Andreas Stylianou, George Minadakis, George M Spyrou, Triantafyllos Stylianopoulos

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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  7. PathIN: an integrated tool for the visualization of pathway interaction networks.Computational and structural biotechnology journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Vasiliki GkretsiBiomedical Sciences Program, Department of Life Sciences, School of Sciences, European University Cyprus, 1516 Nicosia, Cyprus
Maria LoucaCancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, 1678 Nicosia, Cyprus
Andreas StylianouCancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, 1678 Nicosia, Cyprus
George MinadakisBioinformatics Group, The Cyprus Institute of Neurology and Genetics, 2370 Nicosia, Cyprus
George M SpyrouBioinformatics Group, The Cyprus Institute of Neurology and Genetics, 2370 Nicosia, Cyprus
Triantafyllos StylianopoulosCancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, 1678 Nicosia, Cyprus
University of Cyprus · CYCyprus Institute of Neurology and Genetics · CYEuropean University Cyprus · CY

Funding

European Commission Research Executive Agency Grant BIORISE No. 669026European Research Council 336839-ReEngineeringCancer
6 · The paper itself

Abstract

Extracellular matrix (ECM)-related adhesion proteins are important in metastasis. Ras suppressor-1 (RSU-1), a suppressor of

Indexed as

Actin CytoskeletonAdaptor Proteins, Signal TransducingBreast NeoplasmsCalponinsCarrier ProteinsDown-RegulationFemaleGene SilencingGrowth Differentiation Factor 15HumansLIM Domain ProteinsMCF-7 CellsMembrane ProteinsMicrofilament ProteinsNeoplasm InvasivenessProtein Serine-Threonine KinasesAdaptor Proteins, Signal TransducingCalponinsCarrier ProteinsFSCN1 protein, humanGrowth Differentiation Factor 15LIM Domain ProteinsLIMS1 protein, humanMembrane ProteinsMicrofilament ProteinsPARVA protein, humanProtein Serine-Threonine Kinasesrho-Associated KinasesRSU1 protein, humanScaffold Protein ILKTranscription Factorsactin cytoskeletonbioinformaticsFascin-1ILKinvasionPARVAPINCH-1Rho-GTPasesROCK-1

Identifiers

PMID30621163
PMCPMC6337329
OpenAlexW2908500660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.