ReviewNutrients2019
Omega-3 Long-Chain Polyunsaturated Fatty Acids, EPA and DHA: Bridging the Gap between Supply and Demand.
Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
170 citing papers in PubMed, 4 syntheses or guidelines pooled it, 552 citations in OpenAlex.
- Pooled it
- Benefits of the microalgae Spirulina and Schizochytrium in fish nutrition: a meta-analysis.Scientific reports · 2023Pooled it
- Pooled it
- A toolkit for plant lipid engineering: Surveying the efficacies of lipogenic factors for accumulating specialty lipids.Frontiers in plant science · 2022Pooled it
- Oxylipin serum profile changes in response to an open-label anti-inflammatory dietary intervention.Clinical nutrition ESPEN · 2025Trial
- Trial
- Dietary supplementation with seed oil from transgenicThe British journal of nutrition · 2020Trial
- Non-targeted metabolite profiling reveals substantial equivalence of omega-3 enrichedGM crops & food · 2026Article
- Comparison of Physiological Responses to Plant-Protein- and Carbohydrate-Based Fishmeal Substitutes in Largemouth Bass (Animals : an open access journal from MDPI · 2026Article
- Black soldier fly (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Cell-retention for lipid production in continuous Schizochytrium limacinum SR21 cultures fed with dark fermentation effluent.Bioresources and bioprocessing · 2026Article
- Dietary fish oil-corn oil balance modulates growth and metabolic homeostasis of Acrossocheilus fasciatus (Steindachner, 1892) under chronic heat stress.Fish physiology and biochemistry · 2026Article
- Review
- Hormetic dose-response of pure hydroxytyrosol in laying hens: Optimal dose for egg shelf-life extension and yolk docosahexaenoic (DHA) and eicosapentaenoic (EPA) acid concentration.Poultry science · 2026Article
- Making fish oils in plants: from alpha to omega.The New phytologist · 2026Review
- Lipid-Enriched Diet Advances Early Oocyte Development in the EndangeredAnimals : an open access journal from MDPI · 2026Article
- Comparative Analysis of Nutritional Quality, Flavor-Active Amino Acids, and Chromatic Characteristics of Wild and Farmed Red Sea Bream (Foods (Basel, Switzerland) · 2026Article
- Phytohormone supplementation for omega-3 production in microalgae and its potential integration with wastewater cultivation.World journal of microbiology & biotechnology · 2026Review
- Potential of marine dinoflagellates Amphidinium carterae and Prorocentrum minimum as fatty acids producers: A comparative transcriptome and fatty acid profiling study.Journal of microbiology (Seoul, Korea) · 2026Article
- Efficacy of omega-3 fatty acids as a functional food: a multifaceted approach to health reinforcement.Journal of the science of food and agriculture · 2026Review
110 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
The omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA), eicosapentaenoic (EPA, 20:5n-3) and docosahexaenoic (DHA, 22:6n-3) acids, are well accepted as being essential components of a healthy, balanced diet, having beneficial effects on development and in mitigating a range of pathological conditions. However, their global supply from all the traditional sources of these nutrients is insufficient to satisfy human nutritional requirements. For two decades there has been considerable research carried out into all possible alternatives to the main sources of n-3 LC-PUFA, marine fish oil and fishmeal, driven largely by the aquaculture sector, as both the major user and provider of EPA and DHA. In the last few years these efforts have focused increasingly on the development of entirely new supplies of n-3 LC-PUFA produced
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.