Evidence map›Paper›PMID 30621127›Full record

ArticlePharmaceutics2019

Co-Loading of Ascorbic Acid and Tocopherol in Eudragit-Nutriosomes to Counteract Intestinal Oxidative Stress.

Maryam Rezvani, Maria Letizia Manca, Carla Caddeo, Elvira Escribano-Ferrer, Claudia Carbone, José Esteban Peris, Iris Usach, Octavio Diez-Sales, Anna Maria Fadda, Maria Manconi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Formulation and In Vitro Efficacy Assessment ofNanomaterials (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Maryam RezvaniDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, via Ospedale 72, 09124 Cagliari, Italy. maryrezvani.unica@gmail.com.
Maria Letizia MancaDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, via Ospedale 72, 09124 Cagliari, Italy. mlmanca@unica.it.ORCID 0000-0002-3787-257X
Carla CaddeoDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, via Ospedale 72, 09124 Cagliari, Italy. caddeoc@unica.it.
Elvira Escribano-FerrerDepartment of Pharmacy and Pharmaceutical Technology and Physical-Chemistry, Faculty of Pharmacy and Food Science, Institut of Nanoscience and Nanotechnology (IN2UB), University of Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain. eescribano@ub.edu.
Claudia CarboneDepartment of Scienze del Farmaco, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. carbone.claudia@gmail.com.
José Esteban PerisDepartment of Pharmacy, Pharmaceutical Technology and Parasitology, University of Valencia, Avda Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain. Jose.E.Peris@uv.es.
Iris UsachDepartment of Pharmacy, Pharmaceutical Technology and Parasitology, University of Valencia, Avda Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain. Iris.Usach@uv.es.
Octavio Diez-SalesDepartment of Pharmacy, Pharmaceutical Technology and Parasitology, University of Valencia, Avda Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain. octavio.diez@uv.es.
Anna Maria FaddaDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, via Ospedale 72, 09124 Cagliari, Italy. mfadda@unica.it.
Maria ManconiDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, via Ospedale 72, 09124 Cagliari, Italy. manconi@unica.it.ORCID 0000-0003-4818-2344
University of Cagliari · ITUniversitat de València · ESUniversitat de Barcelona · ESUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed at developing a new vesicular formulation capable of promoting the protective effect of ascorbic acid and tocopherol against intestinal oxidative stress damage, and their efficacy in intestinal wound healing upon oral administration. A pH-dependent copolymer (Eudragit

Indexed as

antioxidantEudragitintestinal wound healingNutriosephospholipid vesicles

Identifiers

PMID30621127
PMCPMC6358973
OpenAlexW2907301365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.