Evidence map›Paper›PMID 30621044›Full record

ArticleViruses2019

A Comprehensive RNA-seq Analysis of Human Bocavirus 1 Transcripts in Infected Human Airway Epithelium.

Wei Zou, Min Xiong, Xuefeng Deng, John F Engelhardt, Ziying Yan, Jianming Qiu

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Wei ZouDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA. zouw@umich.edu.
Min XiongThe Children's Mercy Hospital, School of Medicine, University of Missouri Kansas City, Kansas City, MO 64108, USA. xiongminzw@icloud.com.
Xuefeng DengDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA. Xuefeng.Deng@pennmedicine.upenn.edu.
John F EngelhardtDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA. john-engelhardt@uiowa.edu.
Ziying YanDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA. ziying-yan@uiowa.edu.
Jianming QiuDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA. jqiul@kumc.edu.
University of Kansas Medical Center · USUniversity of Iowa · USChildren's Mercy Hospital · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Vector CoreP01HL051670 · NHLBI · UNIVERSITY OF IOWA · PI MCCRAY, PAUL B · 1993 to 2019
$36.5M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
Post-Transcriptional Regulation of Parvovirus Capsid Gene ExpressionR01AI070723 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2007 to 2017
$3.3M
NHLBI NIH HHS P01 HL051670NIAID NIH HHS R01 AI070723NIDDK NIH HHS P30 DK054759NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

Human bocavirus 1 (HBoV1) infects well-differentiated (polarized) human airway epithelium (HAE) cultured at an air-liquid interface (ALI). In the present study, we applied next-generation RNA sequencing to investigate the genome-wide transcription profile of HBoV1, including viral mRNA and small RNA transcripts, in HBoV1-infected HAE cells. We identified novel transcription start and termination sites and confirmed the previously identified splicing events. Importantly, an additional proximal polyadenylation site (pA)p2 and a new distal polyadenylation site (pA)d

Indexed as

Sequence Analysis, RNAAlternative SplicingBronchiCapsid ProteinsCell LineCells, CulturedEpithelial CellsGene Expression ProfilingGene Expression Regulation, ViralGenome, ViralHuman bocavirusHumansPolyadenylationRNA, MessengerRNA, ViralViral Nonstructural ProteinsCapsid ProteinsRNA, MessengerRNA, ViralViral Nonstructural Proteinshuman airway epitheliahuman bocavirus 1parvovirusRNA-seqtranscription profile

Identifiers

PMID30621044
PMCPMC6357044
OpenAlexW2907312846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.