Evidence map›Paper›PMID 30621020›Full record

ReviewCancers2019

Treatment and Prevention of Cancer-Associated Thrombosis in Frail Patients: Tailored Management.

Florian Scotté, Pauline Leroy, Mathilde Chastenet, Laure Aumont, Vidal Benatar, Ismaïl Elalamy

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. Poorer baseline performance status is associated with increased thromboembolism risk in metastatic cancer patients treated with immunotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Florian ScottéDepartment of Medical Oncology and Supportive Care. Hôpital Foch, 92150 Suresnes, France. f.scotte@hopital-foch.com.
Pauline LeroyDepartment of Medical Oncology and Supportive Care. Hôpital Foch, 92150 Suresnes, France. p.leroy@hopital-foch.com.
Mathilde ChastenetDepartment of Medical Oncology and Supportive Care. Hôpital Foch, 92150 Suresnes, France. chastenet.mathilde@gmail.com.
Laure AumontDepartment of Medical Oncology and Supportive Care. Hôpital Foch, 92150 Suresnes, France. l.aumont@hopital-foch.com.
Vidal BenatarHeathics Clinical Consultants. 111 rue des Tennerolles, 92210 Saint-Cloud, France. vidal.benatar@heathics.com.
Ismaïl ElalamyDepartment of Hematology, Hôpital Tenon, Hôpitaux Universitaires de l'Est Parisien, Sorbonne Université, INSERM UMR S938, 75012 Paris, France. ismail.elalamy@aphp.fr.
Hôpital Foch · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced age is one of the major determinants of frailty in patients with cancer-associated thrombosis. However, multiple other factors contribute to frailty in these patients. The identification of frailty in patients with cancer-associated thrombosis is critical as it influences the complexity of the anticoagulant treatment in this population at high risk of venous thromboembolism and bleeding. Factors that contribute to frailty in patients with cancer-associated thrombosis include age, type of cancer, comorbidities such as chronic kidney disease, poly-pharmacotherapy, treatment compliance, cognitive impairment, anemia, thrombocytopenia, mobility, nutritional status, Eastern Cooperative Oncology Group grade, risk of falls, and reduced life expectancy. In the absence of specific clinical studies current anticoagulant treatment guidelines for the management are not fully applicable to frail patients with cancer. The anticoagulant treatment should therefore benefit from a tailored approach based on an algorithm that takes into account the specificities of the malignant disease.

Indexed as

anticoagulantscancercancer-associated thrombosisfrailty

Identifiers

PMID30621020
PMCPMC6356758
OpenAlexW2907532557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.