ArticleCurrent biology : CB2019
Evolution: How Many Phenotypes Do Regulatory Mutations Affect?
Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Profiling human pathogenic repeat expansion regions by synergistic and multi-level impacts on molecular connections.Human genetics · 2023Article
- Sex-specific evolution of a Drosophila sensory system via interacting cis- and trans-regulatory changes.Evolution & development · 2022Article
- Both Binding Strength and Evolutionary Accessibility Affect the Population Frequency of Transcription Factor Binding Sequences in Arabidopsis thaliana.Genome biology and evolution · 2021Article
- Article
- Seven myths of how transcription factors read the cis-regulatory code.Current opinion in systems biology · 2020Article
- On the specificity of gene regulatory networks: How does network co-option affect subsequent evolution?Current topics in developmental biology · 2020Review
- Modular tissue-specific regulation ofDevelopment (Cambridge, England) · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutations in gene regulatory regions are thought to play an important role in the evolution of morphological structures. This is largely due to their minimal pleiotropic effects, limiting their impact to one particular body part. A recent study finds that one such regulatory mutation may affect two particular morphological structures.
Indexed as
Identifiers
30620910What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.