ArticleOrganic letters2019
Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression.
Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed, 50 citations in OpenAlex.
- Natural Products of Freshwater Fungi from a Chemical and Bioactive Perspective.Journal of fungi (Basel, Switzerland) · 2026Review
- Verticillin A-Loaded Surgical Buttresses Prevent Local Pancreatic Cancer Recurrence in a Murine Model.Molecular pharmaceutics · 2025Article
- The apoptotic and anti-proliferative effects of Neosetophomone B in T-cell acute lymphoblastic leukaemia via PI3K/AKT/mTOR pathway inhibition.Cell proliferation · 2025Article
- Article
- Semisynthetic derivatives of the fungal metabolite eupenifeldin via targeting the tropolone hydroxy groups.Bioorganic & medicinal chemistry letters · 2024Article
- New Members of the Centrapalus Coumarin and Pauciflorin Series fromPharmaceutics · 2024Article
- Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway.Cell biology international · 2024Article
- Recent Advances in Chemistry and Antioxidant/Anticancer Biology of Monoterpene and Meroterpenoid Natural Product.Molecules (Basel, Switzerland) · 2024Review
- Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models.Journal of natural products · 2023Article
- Antiglioma Natural Products from the Marine-Associated FungusMolecules (Basel, Switzerland) · 2022Article
- Stereochemical and Biosynthetic Rationalisation of the Tropolone Sesquiterpenoids.Journal of fungi (Basel, Switzerland) · 2022Review
- Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE.Journal of natural products · 2022Article
- Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis.Frontiers in oncology · 2022Article
- Biological activities of meroterpenoids isolated from different sources.Frontiers in pharmacology · 2022Review
- Understanding and Engineering the Stereoselectivity of Humulene Synthase.Angewandte Chemie (International ed. in English) · 2021Article
- Meroterpenoids: A Comprehensive Update Insight on Structural Diversity and Biology.Biomolecules · 2021Review
- Coumarins, dihydroisocoumarins, a dibenzo-Tetrahedron letters · 2021Article
- Peculiarities of meroterpenoids and their bioproduction.Applied microbiology and biotechnology · 2021Review
- Total Synthesis and Computational Investigations of Sesquiterpene-Tropolones Ameliorate Stereochemical Inconsistencies and Resolve an Ambiguous Biosynthetic Relationship.Journal of the American Chemical Society · 2021Article
- Modeling Pharmacokinetic Natural Product-Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach.Pharmacological reviews · 2021Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
Abstract
Six fungal metabolites, of which five were new, including one (1) with a dioxa[4.3.3]propellane ring system, were discovered, identified, and structurally elucidated from Neosetophoma sp. (strain MSX50044); these compounds are similar to the bis-tropolone, eupenifeldin. Three of the meroterpenoids are potent cytotoxic agents against breast, ovarian, mesothelioma, and lung cancer cells with nanomolar IC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.