Evidence map›Paper›PMID 30619967›Full record

ReviewCurrent medical mycology2018

Invasive candidiasis and candidemia in pediatric and neonatal patients: A review of current guidelines.

Eleni Vasileiou, Athanasia Apsemidou, Timoleon-Achilleas Vyzantiadis, Athanasios Tragiannidis

Open access · diamondAbstract readReview
In one paragraph

Review in Current medical mycology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. PediatricJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Congenital Sepsis withMicroorganisms · 2024
    Review
  5. Review
  6. Journal of clinical medicine · 2024
    Review
  7. Article
  8. Antifungals: From Pharmacokinetics to Clinical Practice.Antibiotics (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Plant-Derived Substances in the Fight Against Infections Caused byInternational journal of molecular sciences · 2020
    Review
  11. Clinical practice update of antifungal prophylaxis in immunocompromised children.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Eleni VasileiouHematology Oncology Unit, Pediatric Department of Aristotle University of Thessaloniki, AHEPA General Hospital, Thessaloniki, Greece.
Athanasia ApsemidouDepartment of Internal Medicine, Papanikolaou General Hospital, Thessaloniki, Greece.
Timoleon-Achilleas VyzantiadisDepartment of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Athanasios TragiannidisHematology Oncology Unit, Department of Pediatric, Aristotle University of Thessaloniki, AHEPA General Hospital, Thessaloniki, Greece.
AHEPA University Hospital · GRAristotle University of Thessaloniki · GRG. Papanikolaou General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several international and national guidelines have been proposed for the treatment and prevention of invasive candidiasis/candidemia (IC/C) in both neonatal and pediatric patients. This article is a review of the current guidelines, recommendations, and expert panel consensus of a number of associations and conferences on the prevention and management of IC and candidemia in both pediatric and neonatal patients. The investigated resources included the Infectious Diseases Society of America, the European Conference on Infection in Leukaemia, the European Society of Clinical Microbiology and Infectious Diseases, the German Speaking Mycological Society/Paul-Ehrlich Society for Chemotherapy, as well as the Canadian, Middle Eastern, and Australian guidelines. Echinocandins and liposomal amphotericin B (L-AmB) are the first-line agents in the treatment of IC and candidemia both for immunocompetent and immunocompromised pediatric patients. The recommendations suggested to keep patients under sterile conditions for at least 14 days after blood cultures as the prompt initiation of antifungal treatment. Guidelines addressing the neonates recommended to use L-AmB, deoxycholate AmB (D-AmB), and fluconazole based on three main principles of no previous exposure to azoles, the prompt initiation of antifungal treatment, and control of predisposing underlying conditions. Despite minor differences among the investigated guidelines, general treatment recommendations suggest the prompt initiation of antifungal treatment and control of all predisposing underlying conditions.

Indexed as

CandidemiaChildrenGuidelinesInvasive candidiasisNeonatesPreventionTreatment

Identifiers

PMID30619967
PMCPMC6315202
OpenAlexW2901702878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.