Evidence map›Paper›PMID 30619904›Full record

ReviewBurns & trauma2018

Recent advances of on-demand dissolution of hydrogel dressings.

Hao Lu, Long Yuan, Xunzhou Yu, Chengzhou Wu, Danfeng He, Jun Deng

Abstract readReview
In one paragraph

Review in Burns & trauma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  10. Review
  11. Review
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  15. Growth Factor and Cytokine Delivery Systems for Wound Healing.Cold Spring Harbor perspectives in biology · 2022
    Review
  16. Cohesion mechanisms for bioadhesives.Bioactive materials · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hao LuDepartment of Dermatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400021 China.
Long YuanDepartment of Breast Surgery, Southwest Hospital, Third Military Medical University (Army Medial University), Chongqing, 400038 China.
Xunzhou Yu2Institute of Burn Research, South-West Hospital, State Key Lab of Trauma, Burn and Combined Injury, Third Military Medical University (Army Medical University), Gaotanyan Road No. 30, Shapingba District, Chongqing, 400038 China.
Chengzhou WuDepartment of Respiratory, Wuxi Country People's Hospital, Chongqing, 405800 China.
Danfeng He2Institute of Burn Research, South-West Hospital, State Key Lab of Trauma, Burn and Combined Injury, Third Military Medical University (Army Medical University), Gaotanyan Road No. 30, Shapingba District, Chongqing, 400038 China.
Jun Deng2Institute of Burn Research, South-West Hospital, State Key Lab of Trauma, Burn and Combined Injury, Third Military Medical University (Army Medical University), Gaotanyan Road No. 30, Shapingba District, Chongqing, 400038 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound management is a major global challenge and a big financial burden to the healthcare system due to the rapid growth of chronic diseases including the diabetes, obesity, and aging population. Modern solutions to wound management include hydrogels that dissolve on demand, and the development of such hydrogels is of keen research interest. The formation and subsequent on-demand dissolution of hydrogels is of keen interest to scientists and clinicians. These hydrogels have excellent properties such as tissue adhesion, swelling, and water absorption. In addition, these hydrogels have a distinctive capacity to form in situ and dissolve on-demand via physical or chemical reactions. Some of these hydrogels have been successfully used as a dressing to reduce bleeding in hepatic and aortal models, and the hydrogels remove easily afterwards. However, there is an extremely wide array of different ways to synthesize these hydrogels. Therefore, we summarize here the recent advances of hydrogels that dissolve on demand, covering both chemical cross-linking cases and physical cross-linking cases. We believe that continuous exploration of dissolution strategies will uncover new mechanisms of dissolution and extend the range of applications for hydrogel dressings.

Indexed as

HydrogelOn-demand dissolutionWound dressingWound management

Identifiers

PMID30619904
PMCPMC6310937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.