Evidence map›Paper›PMID 30619633›Full record

ArticleImmune network2018

Obesity-Induced Peritoneal Dissemination of Ovarian Cancer and Dominant Recruitment of Macrophages in Ascites.

Rosa Mistica C Ignacio, Eun-Sook Lee, Andrew J Wilson, Alicia Beeghly-Fadiel, Margaret M Whalen, Deok-Soo Son

Open access · bronzeAbstract read
In one paragraph

Article in Immune network, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Rosa Mistica C IgnacioDepartment of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208, USA.
Eun-Sook LeeDepartment of Pharmaceutical Sciences, College of Pharmacy, Florida A&M University, Tallahassee, FL 32301, USA.
Andrew J WilsonDepartment of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID https://orcid.org/0000-0002-8656-7723
Alicia Beeghly-FadielVanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Margaret M WhalenDepartment of Chemistry, Tennessee State University, Nashville, TN 37209, USA.
Deok-Soo SonDepartment of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208, USA.ORCID https://orcid.org/0000-0001-7981-2076
Meharry Medical College · USVanderbilt University Medical Center · USFlorida Agricultural and Mechanical University · USTennessee State University · US

Funding

Translational Pathology CoreU54CA163069 · NCI · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2011 to 2025
$18.8M
TRAININGU54CA163066 · NCI · TENNESSEE STATE UNIVERSITY · PI MARGARET M WHALEN · 2011 to 2026
$12.8M
Mechanisms associated with neuroprotection from Mn-induced neurotoxicity.R01ES031282 · NIEHS · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI LEE, EUNSOOK YU · 2020 to 2025
$2.4M
Mechanism of manganese-induced impairment of astrocytic glutamate transportersR01ES024756 · NIEHS · MEHARRY MEDICAL COLLEGE · PI LEE, EUN SOOK YU · 2015 to 2019
$1.8M
Roles of inflammation-driven chemokines in the pathogenesis of ovarian cancerSC1AI089073 · NIAID · MEHARRY MEDICAL COLLEGE · PI SON, DEOK-SOO · 2009 to 2013
$1.8M
Roles of proinflammatory chemokines linking obesity and breast cancerSC1CA200519 · NCI · MEHARRY MEDICAL COLLEGE · PI SON, DEOK-SOO · 2015 to 2018
$1.5M
NCI NIH HHS SC1 CA200519NCI NIH HHS U54 CA163066NCI NIH HHS U54 CA163069NIAID NIH HHS SC1 AI089073NIEHS NIH HHS R01 ES024756NIEHS NIH HHS R01 ES031282
6 · The paper itself

Abstract

One-fifth of cancer deaths are associated with obesity. Because the molecular mechanisms by which obesity affects the progression of ovarian cancer (OC) are poorly understood, we investigated if obesity could promote the progression of OC cells using the postmenopausal

Indexed as

AscitesChemokinesMacrophagesObesityOvarian cancer

Identifiers

PMID30619633
PMCPMC6312889
OpenAlexW2908018265

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.