Evidence map›Paper›PMID 30619630›Full record

ArticleImmune network2018

Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD.

Young-Kwan Lee, Ji-Min Ju, Woo-Jeong Shon, Sehwa Oh, Chang-Ki Min, Myung-Soo Kang, Dong-Mi Shin, Eun Young Choi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. IDO1 scavenges reactive oxygen species in myeloid-derived suppressor cells to prevent graft-versus-host disease.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Young-Kwan LeeDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
Ji-Min JuDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
Woo-Jeong ShonDepartment of Food and Nutrition, Seoul National University College of Human Ecology, Seoul 08826, Korea.
Sehwa OhDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
Chang-Ki MinDepartment of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul 06951, Korea.
Myung-Soo KangDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
Dong-Mi ShinDepartment of Food and Nutrition, Seoul National University College of Human Ecology, Seoul 08826, Korea.
Eun Young ChoiDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-2441-3374
Seoul National University · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graft-versus-host disease (GVHD), a life-threatening complication after bone marrow transplantation (BMT), is induced by activation of alloreactive donor T cells. Our previous study demonstrated that transplantation of myeloid differentiation factor 88 (MyD88)-deficient knockout (KO) bone marrow (BM) resulted in aggravation of GVHD. Here, to understand the cellular mechanism, we performed longitudinal

Indexed as

Bone marrow transplantationDendritic cellsGraft-versus-host diseaseMyeloid-derived suppressor cellsMyeloid differentiation factor 88

Identifiers

PMID30619630
PMCPMC6312895
OpenAlexW2906267938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.