Evidence map›Paper›PMID 30619327›Full record

ArticleFrontiers in immunology2018

Oral Passive Immunization With Plasma-Derived Polyreactive Secretory-Like IgA/M Partially Protects Mice Against Experimental Salmonellosis.

Blaise Corthésy, Justine Monnerat, Marius Lötscher, Cédric Vonarburg, Alexander Schaub, Gilles Bioley

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Recombinant Human Secretory IgA InducesACS infectious diseases · 2021
    Article
  6. Article
  7. Article
  8. IgA: Structure, Function, and Developability.Antibodies (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Blaise CorthésyR&D Laboratory, Division of Immunology and Allergy, Lausanne University Hospital (CHUV), Épalinges, Switzerland.
Justine MonneratR&D Laboratory, Division of Immunology and Allergy, Lausanne University Hospital (CHUV), Épalinges, Switzerland.
Marius LötscherResearch Department, CSL Behring AG, Bern, Switzerland.
Cédric VonarburgResearch Department, CSL Behring AG, Bern, Switzerland.
Alexander SchaubResearch Department, CSL Behring AG, Bern, Switzerland.
Gilles BioleyR&D Laboratory, Division of Immunology and Allergy, Lausanne University Hospital (CHUV), Épalinges, Switzerland.
CSL (Switzerland) · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secretory immunoglobulins have a critical role in defense of the gastrointestinal tract and are known to act by preventing bacterial acquisition. A stringent murine model of bacterial infection with

Indexed as

Administration, OralAnimalsDisease Models, AnimalFemaleHumansImmunization, PassiveImmunoglobulin A, SecretoryImmunoglobulin MIntestinal MucosaMiceMice, Inbred BALB CPeyer's PatchesPlasmaSalmonella InfectionsSalmonella typhimuriumTreatment OutcomeImmunoglobulin A, SecretoryImmunoglobulin Mpassive immunizationprotectionSalmonellasecretory IgAsecretory IgM

Identifiers

PMID30619327
PMCPMC6305475
OpenAlexW2905476886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.