Evidence map›Paper›PMID 30619306›Full record

ReviewFrontiers in immunology2018

The Wonder Years: What Can Primary School Children Teach Us About Immunity to

James A Seddon, Silvia S Chiang, Hanif Esmail, Anna K Coussens

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.

  1. Pooled it
  2. Timing ofThorax · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinical characteristics and risk factors of severe pulmonary tuberculosis in children in Yunnan, China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  8. Article
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  12. Article
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  15. Review
  16. Article
  17. Observational
  18. Article
  19. Tuberculous Meningitis Across the Lifespan.The Journal of infectious diseases · 2025
    Review
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

James A SeddonDepartment of Paediatrics, Imperial College London, London, United Kingdom.
Silvia S ChiangDepartment of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, United States.
Hanif EsmailRadcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Anna K CoussensWellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Imperial College London · GBRhode Island Hospital · USWalter and Eliza Hall Institute of Medical Research · AUWellcome Centre for Infectious Diseases Research in Africa · ZA

Funding

Validation and Application of a Model for Human-like TB Latency in RabbitsU19AI111276 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI ALLAND, DAVID, ELLNER, JERROLD J. · 2014 to 2020
$23.3M
Teens on TB Treatment: Predicting Adherence through Clinical Decision AnalysisK01TW010829 · FIC · RHODE ISLAND HOSPITAL · PI CHIANG, SILVIA SHINPEI · 2017 to 2021
$775k
FIC NIH HHS K01 TW010829Medical Research Council MR/R007942/1NIAID NIH HHS L40 AI141492NIAID NIH HHS U19 AI111276
6 · The paper itself

Abstract

In high burden settings, the risk of infection with

Indexed as

AdolescentAdultAge FactorsChildDisease ProgressionHost-Pathogen InteractionsHumansImmunity, InnateIncidenceMycobacterium tuberculosisSex FactorsSexual MaturationTuberculosisTuberculosis VaccinesYoung AdultTuberculosis VaccinesadolescencechildrenimmunityinfectionMycobacterium tuberculosisprotectiontuberculosisvaccination

Identifiers

PMID30619306
PMCPMC6300506
OpenAlexW2904268068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.