Evidence map›Paper›PMID 30619289›Full record

ArticleFrontiers in immunology2018

Interleukin-4 Receptor Alpha Expressing B Cells Are Essential to Down-Modulate Host Granulomatous Inflammation During Schistosomasis.

Hlumani Ndlovu, Justin Komguep Nono, Nada Abdel Aziz, Natalie Eva Nieuwenhuizen, Frank Brombacher

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Differential murine responses toInfection and immunity · 2024
    Article
  2. Food and waterborne parasitology · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Hlumani NdlovuInternational Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component, Cape Town, South Africa.
Justin Komguep NonoInternational Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component, Cape Town, South Africa.
Nada Abdel AzizInternational Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component, Cape Town, South Africa.
Natalie Eva NieuwenhuizenInternational Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component, Cape Town, South Africa.
Frank BrombacherInternational Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component, Cape Town, South Africa.
Wellcome Centre for Infectious Diseases Research in Africa · ZAInternational Centre for Genetic Engineering and Biotechnology · ZAUniversity of Cape Town · ZA

Funding

Wellcome Trust
6 · The paper itself

Abstract

Schistosomiasis (bilharzia) is a parasitic helminth disease that can cause severe inflammatory pathology leading to organ damage in humans. Failure of the host to regulate egg-driven granulomatous inflammation causes host morbidity during chronic infection with

Indexed as

AnimalsB-LymphocytesDisease Models, AnimalFemaleHumansInflammationInterleukin-4 Receptor alpha SubunitIntestinesLiverLungMaleMiceMice, Inbred BALB CMice, TransgenicReceptors, Cell SurfaceSchistosoma mansoniIl4ra protein, mouseInterleukin-4 Receptor alpha SubunitReceptors, Cell SurfaceB cellschronic infectionIL-4RApathologyschistosomiais

Identifiers

PMID30619289
PMCPMC6305417
OpenAlexW2905433903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.