Evidence map›Paper›PMID 30619273›Full record

ReviewFrontiers in immunology2018

Immunomodulation of the Tumor Microenvironment: Turn Foe Into Friend.

Hanne Locy, Sven de Mey, Wout de Mey, Mark De Ridder, Kris Thielemans, Sarah K Maenhout

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 311 citations in OpenAlex.

  1. Trial
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  3. Designing lysate-based hydrogels for on-demand therapy.Journal of pharmaceutical analysis · 2026
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  12. Robust CD8Frontiers in immunology · 2026
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  18. NCellular and molecular life sciences : CMLS · 2025
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97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hanne LocyLaboratory of Molecular and Cellular Therapy (LMCT), Vrije Universiteit Brussel, Brussels, Belgium.
Sven de MeyDepartment of Radiotherapy, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Wout de MeyLaboratory of Molecular and Cellular Therapy (LMCT), Vrije Universiteit Brussel, Brussels, Belgium.
Mark De RidderDepartment of Radiotherapy, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Kris ThielemansLaboratory of Molecular and Cellular Therapy (LMCT), Vrije Universiteit Brussel, Brussels, Belgium.
Sarah K MaenhoutLaboratory of Molecular and Cellular Therapy (LMCT), Vrije Universiteit Brussel, Brussels, Belgium.
Vrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy, where the patient's own immune system is exploited to eliminate tumor cells, has become one of the most prominent new cancer treatment options in the last decade. The main hurdle for classical cancer vaccines is the need to identify tumor- and patient specific antigens to include in the vaccine. Therefore,

Indexed as

Cancer VaccinesHumansImmunologic FactorsImmunomodulationImmunotherapyNeoplasmsPhotochemotherapyReproducibility of ResultsTumor MicroenvironmentVaccinationCancer VaccinesImmunologic Factorscancerimmunotherapyin situ vaccinationoncolytic virotherapyradiotherapy

Identifiers

PMID30619273
PMCPMC6297829
OpenAlexW2904370205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.