Evidence map›Paper›PMID 30619265›Full record

Observational studyFrontiers in immunology2018

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection.

Matthew K O'Shea, Thomas E Fletcher, Julius Muller, Rachel Tanner, Magali Matsumiya, J Wendi Bailey, Jayne Jones, Steven G Smith, Gavin Koh, William G Horsnell and 5 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Frontiers in immunology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Induction of Siglec-FFrontiers in immunology · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. TheF1000Research · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Matthew K O'SheaNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Thomas E FletcherRoyal Centre for Defence Medicine, Joint Medical Command, Birmingham, United Kingdom.
Julius MullerNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Rachel TannerNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Magali MatsumiyaNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
J Wendi BaileyDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Jayne JonesDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Steven G SmithDepartment of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Gavin KohDepartment of Infectious Diseases, Northwick Park Hospital, London, United Kingdom.
William G HorsnellInstitute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.
Nicholas J BeechingDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
James DunbarRoyal Centre for Defence Medicine, Joint Medical Command, Birmingham, United Kingdom.
Duncan WilsonRoyal Centre for Defence Medicine, Joint Medical Command, Birmingham, United Kingdom.
Adam F CunninghamInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Helen McShaneNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Liverpool School of Tropical Medicine · GBUniversity of Oxford · GBRoyal Navy · GBUniversity of Birmingham · GBJenner Institute · GBLondon School of Hygiene & Tropical Medicine · GBNorthwick Park Hospital · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Soil-transmitted helminths and

Indexed as

AdolescentAncylostomatoideaAnimalsEosinophilsFecesGene Expression ProfilingHookworm InfectionsHumansLatent TuberculosisLongitudinal StudiesMaleMycobacterium tuberculosisNepalProspective StudiesRisk FactorsYoung Adulteosinophilgrowth inhibitionhookwormlatent tuberculosisLTBItuberculosis

Identifiers

PMID30619265
PMCPMC6302045
OpenAlexW2905479114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.