Evidence map›Paper›PMID 30618857›Full record

ArticleFrontiers in psychiatry2018

Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures.

Claire F Durant, Louise M Paterson, Sam Turton, Susan J Wilson, James F M Myers, Suresh Muthukumaraswamy, Ashwin Venkataraman, Inge Mick, Susan Paterson, Tessa Jones and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. The neurobiological markers of acute alcohol's subjective effects in humans.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Trial
  2. Trial
  3. GABAMedComm · 2025
    Review
  4. Article
  5. A compendium of validated pain genes.WIREs mechanisms of disease · 2022
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Claire F DurantNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Louise M PatersonNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Sam TurtonNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Susan J WilsonNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
James F M MyersNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Suresh MuthukumaraswamyToxicology Unit, Imperial College London, London, United Kingdom.
Ashwin VenkataramanNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Inge MickNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Susan PatersonCentre for Brain Science, University of Auckland, Auckland, New Zealand.
Tessa JonesNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Limon K NaharCentre for Brain Science, University of Auckland, Auckland, New Zealand.
Rosa E CorderoCentre for Brain Science, University of Auckland, Auckland, New Zealand.
David J NuttNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Anne Lingford-HughesNeuropsychopharmacology Unit, Division of Brain Sciences, Department of Medicine, Centre for Psychiatry, Imperial College London, London, United Kingdom.
Imperial College London · GBUniversity of Auckland · NZ

Funding

Medical Research Council G0400575Medical Research Council G1002226Medical Research Council MR/N00616X/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

addictionalcohol use disorder (AUD)baclofen (PubChem CID: 2284)EEGGABA-B receptorgrowth hormonepharmacodynamic (PD)pharmacokinetic (PK)

Identifiers

PMID30618857
PMCPMC6302106
OpenAlexW2904414284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.