ArticleFrontiers in psychiatry2018
Parallel Changes in Mood and Melatonin Rhythm Following an Adjunctive Multimodal Chronobiological Intervention With Agomelatine in People With Depression: A Proof of Concept Open Label Study.
Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Circadian realignment and depressed mood: A systematic review.Sleep medicine reviews · 2025Pooled it
- Hypnotic and Melatonin/Melatonin-Receptor Agonist Treatment in Bipolar Disorder: A Systematic Review and Meta-Analysis.CNS drugs · 2022Pooled it
- Agomelatine in pediatric patients with moderate to severe major depressive disorder: an open-label extension study.European child & adolescent psychiatry · 2025Trial
- Change in circadian preference predicts sustained treatment outcomes in patients with unipolar depression and evening preference.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Associations of Circadian Rhythms with Cognitive Performance in Patients with Amnestic Mild Cognitive Impairment (aMCI).Journal of clinical medicine · 2026Article
- Cortisol Detection Methods and the Hormone's Role in Evaluating Circadian Rhythm Disruption.International journal of molecular sciences · 2025Review
- From Rhythm to Relief: Heart Rate Variability as a Window into Anhedonia Response During Agomelatine Treatment in Major Depressive Disorder.Medicina (Kaunas, Lithuania) · 2025Article
- Circadian rhythms of melatonin and its relationship with anhedonia in patients with mood disorders: a cross-sectional study.BMC psychiatry · 2024Article
- Review
- Article
- Nonlinear relationship between sleep midpoint and depression symptoms: a cross-sectional study of US adults.BMC psychiatry · 2023Article
- Does circadian dysrhythmia drive the switch into high- or low-activation states in bipolar I disorder?Bipolar disorders · 2023Review
- Circadian Disruption and Mental Health: The Chronotherapeutic Potential of Microbiome-Based and Dietary Strategies.International journal of molecular sciences · 2023Review
- Agomelatine: a potential novel approach for the treatment of memory disorder in neurodegenerative disease.Neural regeneration research · 2023Review
- Rest-activity rhythm associated with depressive symptom severity and attention among patients with major depressive disorder: a 12-month follow-up study.Frontiers in psychiatry · 2023Article
- Can melatonin reduce the severity of post-COVID-19 syndrome?EXCLI journal · 2023Review
- Article
- Disrupted circadian rhythms and mental health.Handbook of clinical neurology · 2021Review
- Glymphatic Dysfunction: A Bridge Between Sleep Disturbance and Mood Disorders.Frontiers in psychiatry · 2021Article
- Chronobiology Revisited in Psychiatric Disorders: From a Translational Perspective.Psychiatry investigation · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.