ReviewFrontiers in physiology2018
Dendritic and Axonal Propagation Delays May Shape Neuronal Networks With Plastic Synapses.
Review in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Article
- Encoding under time pressure: stages and electrophysiological mechanisms in facial expression processing.Neuroreport · 2026Article
- Amplifying post-stimulation oscillatory dynamics by engaging synaptic plasticity with transcranial alternating current stimulation.Frontiers in network physiology · 2025Article
- Time delays in computational models of neuronal and synaptic dynamics.Frontiers in computational neuroscience · 2025Article
- Emergence of complex oscillatory dynamics in the neuronal networks with long activity time of inhibitory synapses.iScience · 2024Article
- Synchronization of delayed coupled neurons with multiple synaptic connections.Cognitive neurodynamics · 2024Article
- Dynamics of parkinsonian oscillations mediated by transmission delays in a mean-field model of the basal ganglia.Frontiers in cellular neuroscience · 2024Article
- Physiological features of parvalbumin-expressing GABAergic interneurons contributing to high-frequency oscillations in the cerebral cortex.Current research in neurobiology · 2024Review
- Selective control of synaptic plasticity in heterogeneous networks through transcranial alternating current stimulation (tACS).PLoS computational biology · 2023Article
- Delay-dependent transitions of phase synchronization and coupling symmetry between neurons shaped by spike-timing-dependent plasticity.Cognitive neurodynamics · 2023Article
- Decoupling of interacting neuronal populations by time-shifted stimulation through spike-timing-dependent plasticity.PLoS computational biology · 2023Article
- Targeted neuroplasticity in spatiotemporally patterned invasive neuromodulation therapies for improving clinical outcomes.Frontiers in neuroinformatics · 2023Article
- Precise Spiking Motifs in Neurobiological and Neuromorphic Data.Brain sciences · 2022Review
- Synaptic reshaping of plastic neuronal networks by periodic multichannel stimulation with single-pulse and burst stimuli.PLoS computational biology · 2022Article
- Therapeutic Neuromodulation toward a Critical State May Serve as a General Treatment Strategy.Biomedicines · 2022Article
- Critical Parameters in Dynamic Network Modeling of Sepsis.Frontiers in network physiology · 2022Article
- The Origin of Abnormal Beta Oscillations in the Parkinsonian Corticobasal Ganglia Circuits.Parkinson's disease · 2022Review
- Inhibitory Spike-Timing-Dependent Plasticity Can Account for Pathological Strengthening of Pallido-Subthalamic Synapses in Parkinson's Disease.Frontiers in physiology · 2022Article
- Dopamine Receptors: Is It Possible to Become a Therapeutic Target for Depression?Frontiers in pharmacology · 2022Review
- Efficient suppression of parkinsonian beta oscillations in a closed-loop model of deep brain stimulation with amplitude modulation.Frontiers in human neuroscience · 2022Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Biological neuronal networks are highly adaptive and plastic. For instance, spike-timing-dependent plasticity (STDP) is a core mechanism which adapts the synaptic strengths based on the relative timing of pre- and postsynaptic spikes. In various fields of physiology, time delays cause a plethora of biologically relevant dynamical phenomena. However, time delays increase the complexity of model systems together with the computational and theoretical analysis burden. Accordingly, in computational neuronal network studies propagation delays were often neglected. As a downside, a classic STDP rule in oscillatory neurons without propagation delays is unable to give rise to bidirectional synaptic couplings, i.e., loops or uncoupled states. This is at variance with basic experimental results. In this mini review, we focus on recent theoretical studies focusing on how things change in the presence of propagation delays. Realistic propagation delays may lead to the emergence of neuronal activity and synaptic connectivity patterns, which cannot be captured by classic STDP models. In fact, propagation delays determine the inventory of attractor states and shape their basins of attractions. The results reviewed here enable to overcome fundamental discrepancies between theory and experiments. Furthermore, these findings are relevant for the development of therapeutic brain stimulation techniques aiming at shifting the diseased brain to more favorable attractor states.
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