ArticleFrontiers in physiology2018
Forced Swim Reliability for Exercise Testing in Rats by a Tethered Swimming Apparatus.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- The response of glutathione oxidase and cytochromeBiochemistry and biophysics reports · 2025Article
- Light-Sheet Fluorescence Imaging Reveals Three-Dimensional Amyloid Burden Reduction Following Five Weeks of Swimming Exercise in Alzheimer's Mouse.International journal of molecular sciences · 2025Article
- Design of Antioxidant Nanoparticle, which Selectively Locates and Scavenges Reactive Oxygen Species in the Gastrointestinal Tract, Increasing The Running Time of Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Hypoxia modeling techniques: A review.Heliyon · 2023Review
- Nicotinamide riboside-A missing piece in the puzzle of exercise therapy for older adults?Experimental gerontology · 2020Review
- Oral treatment with the Chinese herbal supplements B307 enhances muscle endurance of ICR mice after exhaustive swimming via suppressing fatigue, oxidative stress, and inflammation.Food science & nutrition · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess the physical capacity of rats in forced swim tests, the animal should perform a continuous activity (CON) at the surface to avoid apnea. Bobbing movement (BOB), vigorous paddling known as climbing (CLI), and diving activity (DIV) are inadequate swimming patterns known to increase the exercise intensity variability, impairing the test reliability. Thus, the exercise work accomplished and related physiological variables, such as the blood lactate concentration, may be unreproducible in forced swim. This study aimed to verify the exercise work reproducibility in rats with a 30-min test-retest at maximal lactate steady state (MLSS) intensity using a tethered-swimming apparatus that analyzes swimming patterns by the direct measurement of swimming force. Additionally, it was determined the swimming force and duration of CON, BOB, CLI, and DIV at physiologically different exercise-intensities. The swimming force at MLSS (
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