Evidence map›Paper›PMID 30618826›Full record

ArticleFrontiers in physiology2018

Epidural Spinal Cord Stimulation Acutely Modulates Lower Urinary Tract and Bowel Function Following Spinal Cord Injury: A Case Report.

Matthias Walter, Amanda H X Lee, Alex Kavanagh, Aaron A Phillips, Andrei V Krassioukov

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06845904 (Study on Preliminary Safety and Efficacy of Epidural Electrical Stimulation to Manage Lower Urinary Tract Dysfunction After Spinal Cord Injury), which is not on this map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06845904 narecruitingnot on this mapstarted 2025, after this paper: background citation

Study on Preliminary Safety and Efficacy of Epidural Electrical Stimulation to Manage Lower Urinary Tract Dysfunction After Spinal Cord Injury

TypeinterventionalSponsorEcole Polytechnique Fédérale de LausanneRan2025 to 2027Enrolled3ConditionsSpinal Cord Injuries (SCI), Spinal Cord InjuryArmsWaveWriter Alpha™ neurostimulation system
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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  17. Mapping the Iceberg of Autonomic Recovery: Mechanistic Underpinnings of Neuromodulation following Spinal Cord Injury.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Matthias WalterInternational Collaboration on Repair Discoveries, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
Amanda H X LeeInternational Collaboration on Repair Discoveries, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
Alex KavanaghDepartment of Urologic Sciences, The University of British Columbia, Vancouver, BC, Canada.
Aaron A PhillipsDepartment of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Andrei V KrassioukovInternational Collaboration on Repair Discoveries, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
International Collaboration On Repair Discoveries · CAUniversity of British Columbia · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regaining control of autonomic functions such as those of the cardiovascular system, lower urinary tract and bowel, rank among the most important health priorities for individuals living with spinal cord injury (SCI). Recently our research provided evidence that epidural spinal cord stimulation (ESCS) could acutely modulate autonomic circuits responsible for cardiovascular function after SCI. This finding raised the question of whether ESCS can be used to modulate autonomic circuits involved in lower urinary tract and bowel control after SCI. We present the case of a 32-year-old man with a chronic motor-complete SCI (American Spinal injury Association Impairment Scale B) at the 5

Indexed as

epidural spinal cord stimulationneurogenic bowel dysfunctionneurogenic lower urinary tract dysfunctionspinal cord injuryurodynamic investigation

Identifiers

PMID30618826
PMCPMC6305431
OpenAlexW2905848137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.