ArticleFrontiers in physiology2018
Cortical and Subcortical Neural Correlates for Respiratory Sensation in Response to Transient Inspiratory Occlusions in Humans.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Broca's area, responsible for speech production, is regulated by lung function.Neural regeneration research · 2026Article
- Resting-state fMRI using hidden Markov models reveals abnormal dynamic brain functional states in asthma.Scientific reports · 2026Article
- Asthma: Biomedical and Psychobiological Perspectives.Biopsychosocial science and medicine · 2025Review
- The Neuroanatomical Correlates of Dyspnea: An Activation Likelihood Estimation Meta-Analysis.NeuroSci · 2025Review
- COPD, PRISm and lung function reduction affect the brain cortical structure: a Mendelian randomization study.BMC pulmonary medicine · 2024Article
- Efficacy and cerebral mechanisms of acupuncture for chronic obstructive pulmonary disease: study protocol for a multicenter, randomized controlled neuroimaging trial.Frontiers in neurology · 2024Article
- Cortical Sources of Respiratory Mechanosensation, Laterality, and Emotion: An MEG Study.Brain sciences · 2022Article
- The impact of emotional context on neural substrates of respiratory sensory gating.Frontiers in neuroscience · 2022Article
- Investigation on the Effect of Oral Breathing on Cognitive Activity Using Functional Brain Imaging.Healthcare (Basel, Switzerland) · 2021Article
- Heart Rate and Respiration Affect the Functional Connectivity of Default Mode Network in Resting-State Functional Magnetic Resonance Imaging.Frontiers in neuroscience · 2020Article
- The effect of anxiety on brain activation patterns in response to inspiratory occlusions: an fMRI study.Scientific reports · 2019Article
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortical and subcortical mechanosensation of breathing can be measured by short respiratory occlusions. However, the corresponding neural substrates involved in the respiratory sensation elicited by a respiratory mechanical stimulus remained unclear. Therefore, we applied the functional magnetic resonance imaging (fMRI) technique to study cortical activations of respiratory mechanosensation. We hypothesized that thalamus, frontal cortex, somatosensory cortex, and inferior parietal cortex would be significantly activated in response to respiratory mechanical stimuli. We recruited 23 healthy adults to participate in our event-designed fMRI experiment. During the 12-min scan, participants breathed with a specialized face-mask. Single respiratory occlusions of 150 ms were delivered every 2-4 breaths. At least 32 successful occlusions were collected for data analysis. The results showed significant neural activations in the thalamus, supramarginal gyrus, middle frontal gyrus, inferior frontal triangularis, and caudate (AlphaSim corrected
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