Evidence map›Paper›PMID 30618796›Full record

ArticleFrontiers in physiology2018

Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans.

Berenice Otero-Díaz, Marcela Rodríguez-Flores, Verónica Sánchez-Muñoz, Fernando Monraz-Preciado, Samuel Ordoñez-Ortega, Vicente Becerril-Elias, Guillermina Baay-Guzmán, Rodolfo Obando-Monge, Eduardo García-García, Berenice Palacios-González and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07263126 (Effect of Bicycle Ergometer Training in Thermoneutral and Lightly Cold Ambient Temperatures on Fat Tissue Amount and Metabolism in Overweight and Obese Women), which is not on this map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07263126 nacompletednot on this mapstarted 2025, after this paper: background citation

Effect of Bicycle Ergometer Training in Thermoneutral and Lightly Cold Ambient Temperatures on Fat Tissue Amount and Metabolism in Overweight and Obese Women

TypeinterventionalSponsorPamukkale UniversityRan2025 to 2026Enrolled36ConditionsEndurance TrainingArmsendurance training with bicycle ergometer in termoneutral ambient temperature, endurance training with bicycle ergometer in lightly cold ambient temperature
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
  2. Chronic cold induces some similar effects to endurance exercise on body morphometrics and skeletal muscle structure in rats.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. The Role of Exercise in Fat Oxidation and Its Impact on Adolescent Metabolism.Advances in experimental medicine and biology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Lactate shuttling drives the browning of white adipose tissue after burn.American journal of physiology. Endocrinology and metabolism · 2023
    Article
  17. Exercise-induced regulation of adipose tissue.Current opinion in genetics & development · 2023
    Review
  18. Article
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Berenice Otero-DíazLaboratorio de Genómica de Enfermedades Cardiovasculares, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Marcela Rodríguez-FloresDepartamento de Endocrinología, Clínica de Obesidad y Trastornos de la Conducta Alimentaria, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Verónica Sánchez-MuñozCentro de Nutrición y Obesidad, The American British Cowdray (ABC) Medical Center, Mexico City, Mexico.
Fernando Monraz-PreciadoDepartamento de Cirugía, Servicio de Cirugía Endocrina y Laparoscopia Avanzada, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Samuel Ordoñez-OrtegaDepartamento de Cirugía, Servicio de Cirugía Endocrina y Laparoscopia Avanzada, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Vicente Becerril-EliasUnidad de Investigación en Enfermedades Oncológicas, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Guillermina Baay-GuzmánUnidad de Investigación en Enfermedades Oncológicas, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Rodolfo Obando-MongeLaboratorio de Genómica de Enfermedades Cardiovasculares, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Eduardo García-GarcíaDepartamento de Endocrinología, Clínica de Obesidad y Trastornos de la Conducta Alimentaria, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Berenice Palacios-GonzálezUnidad de Vinculación Científica, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
María Teresa Villarreal-MolinaLaboratorio de Genómica de Enfermedades Cardiovasculares, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Mauricio Sierra-SalazarDepartamento de Cirugía, Servicio de Cirugía Endocrina y Laparoscopia Avanzada, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Barbara Antuna-PuenteLaboratorio de Genómica de Enfermedades Cardiovasculares, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXNational Institute of Genomic Medicine · MXHospital Infantil de México Federico Gómez · MXCentro Médico ABC · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the effect of exercise on white adipose tissue browning and metabolic improvement in rodents is clear, there are few studies in humans with inconclusive results. Thus, the aim of the study was to assess whether an exercise intervention promotes subcutaneous adipose tissue browning in humans, and whether this response is associated with metabolic improvement in three groups of individuals defined by body mass index (BMI) (kg/m

Indexed as

adipokinesadipose tissuebrowninginsulin sensitivitymyokinesphysical activity

Identifiers

PMID30618796
PMCPMC6297830
OpenAlexW2904162642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.