Evidence map›Paper›PMID 30618617›Full record

ReviewFrontiers in molecular neuroscience2018

The Complex Conformational Dynamics of Neuronal Calcium Sensor-1: A Single Molecule Perspective.

Dhawal Choudhary, Birthe B Kragelund, Pétur O Heidarsson, Ciro Cecconi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Optical Tweezers Exploring Neuroscience.Frontiers in bioengineering and biotechnology · 2020
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Dhawal ChoudharyDepartment of Physics, Informatics and Mathematics, University of Modena and Reggio Emilia, Modena, Italy.
Birthe B KragelundStructural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Pétur O HeidarssonDepartment of Biochemistry, University of Zurich, Zurich, Switzerland.
Ciro CecconiDepartment of Physics, Informatics and Mathematics, University of Modena and Reggio Emilia, Modena, Italy.
University of Modena and Reggio Emilia · ITUniversity of Copenhagen · DKUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human neuronal calcium sensor-1 (NCS-1) is a multispecific two-domain EF-hand protein expressed predominantly in neurons and is a member of the NCS protein family. Structure-function relationships of NCS-1 have been extensively studied showing that conformational dynamics linked to diverse ion-binding is important to its function. NCS-1 transduces Ca

Indexed as

calcium bindingNCS-1optical tweezersprotein folding and misfoldingsingle molecule studies

Identifiers

PMID30618617
PMCPMC6304440
OpenAlexW2905274784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.