Evidence map›Paper›PMID 30618544›Full record

ArticleFrontiers in neuroscience2018

Tuning Neuromodulation Effects by Orientation Selective Deep Brain Stimulation in the Rat Medial Frontal Cortex.

Lauri J Lehto, Pavel Filip, Hanne Laakso, Alejandra Sierra, Julia P Slopsema, Matthew D Johnson, Lynn E Eberly, Walter C Low, Olli Gröhn, Heikki Tanila and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Neuromodulation in Small Animal fMRI.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Silent zero TE MR neuroimaging: Current state-of-the-art and future directions.Progress in nuclear magnetic resonance spectroscopy · 2021
    Review
  11. Article
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Lauri J LehtoCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
Pavel FilipCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
Hanne LaaksoCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
Alejandra SierraA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Julia P SlopsemaDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States.
Matthew D JohnsonDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States.
Lynn E EberlyDivision of Biostatistics, University of Minnesota, Minneapolis, MN, United States.
Walter C LowDepartment of Neurosurgery, University of Minnesota, Minneapolis, MN, United States.
Olli GröhnA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Heikki TanilaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Silvia MangiaCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
Shalom MichaeliCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
University of Minnesota · USUniversity of Eastern Finland · FIResonance Research (United States) · USMasaryk University · CZ

Funding

NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Spatiotemporal Optimization of Deep Brain Stimulation for Parkinson's DiseaseR01NS094206 · NINDS · UNIVERSITY OF MINNESOTA · PI Matthew Douglas Johnson, THEODEN I NETOFF · 2016 to 2026
$5.6M
High density multielectrode arrays with spatially selective unidirectional and rotating fields for investigation of neuronal networksU01NS103569 · NINDS · UNIVERSITY OF MINNESOTA · PI MICHAELI, SHALOM · 2017 to 2019
$3.7M
NIBIB NIH HHS P41 EB015894NINDS NIH HHS R01 NS094206NINDS NIH HHS U01 NS103569
6 · The paper itself

Abstract

Previous studies that focused on treating major depressive disorder with conventional deep brain stimulation (DBS) paradigms produced inconsistent results. In this proof-of-concept preclinical study in rats (

Indexed as

deep brain stimulationdepressionfMRIinfralimbic cortexorientation selective

Identifiers

PMID30618544
PMCPMC6300504
OpenAlexW2905490746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.