Evidence map›Paper›PMID 30618520›Full record

ReviewPostepy dermatologii i alergologii2018

Cutaneous mastocytosis treatment: strategies, limitations and perspectives.

Justyna Czarny, Magdalena Lange, Hanna Ługowska-Umer, Roman J Nowicki

Open access · goldAbstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cutaneous mastocytosis in childhood.Allergologie select · 2022
    Review
  8. Review
  9. Article
  10. Review
  11. Long-Term Successful Treatment of Indolent Systemic Mastocytosis With Omalizumab.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2021
    Article
  12. Pediatric Mastocytosis: An Update.Mediterranean journal of hematology and infectious diseases · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Justyna CzarnyDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Magdalena LangeDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Hanna Ługowska-UmerDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Roman J NowickiDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastocytosis is a rare myeloproliferative disease, characterized by excessive proliferation and accumulation of mast cells in the tissues. In cutaneous mastocytosis (CM), mast cells infiltration is limited to the skin, whereas in systemic mastocytosis (SM) internal organs are involved. The first-line treatment in CM is antimediator therapy (mainly H1 and H2 antihistamines) and short-term topical corticosteroids. Phototherapy is the second-line therapy which may be considered when antihistamines do not produce the expected improvement. New therapeutic options include omalizumab and KIT-targeting agents. Although the disappearance of skin lesions has been reported as a result of cytoreductive therapies in SM, the use of potentially toxic drugs in CM is not recommended. In all adults with mastocytosis and in pediatric patients with severe CM, a persistently elevated serum tryptase level and anaphylaxis in medical history, equipping with epinephrine autoinjector for use in case of anaphylaxis is recommended.

Indexed as

mastocytosisprophylaxistreatment

Identifiers

PMID30618520
PMCPMC6320483
OpenAlexW2905264782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.