ArticleEpigenomics2019
Measured maternal prepregnancy anthropometry and newborn DNA methylation.
Article in Epigenomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium.Science advances · 2024Pooled it
- DNA methylation changes in cord blood and the developmental origins of health and disease - a systematic review and replication study.BMC genomics · 2022Pooled it
- Trial
- Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis.Clinical epigenetics · 2020Trial
- Maternal fatty acid concentrations and newborn DNA methylation.The American journal of clinical nutrition · 2020Trial
- Examination of newborn DNA methylation among women with polycystic ovary syndrome/hirsutism.Epigenetics · 2023Article
- Gestational Weight Gain Relates to DNA Methylation in Umbilical Cord, Which, In Turn, Associates with Offspring Obesity-Related Parameters.Nutrients · 2023Article
- Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways.Cardiovascular diabetology · 2023Article
- Maternal caffeine intake and DNA methylation in newborn cord blood.The American journal of clinical nutrition · 2022Article
- The neonatal PROC gene rs1799809 polymorphism modifies the association between prenatal air pollutants exposure and PROC promoter methylation.Environmental science and pollution research international · 2022Article
- Periconception and Prenatal Exposure to Maternal Perceived Stress and Cord Blood DNA Methylation.Epigenetics insights · 2022Article
- Conception by fertility treatment and offspring deoxyribonucleic acid methylation.Fertility and sterility · 2021Article
- Parental Weight Status and Offspring Behavioral Problems and Psychiatric Symptoms.The Journal of pediatrics · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
aimWe examined maternal prepregnancy anthropometry and cord blood DNA methylation.
methodsAssociations between maternal measures (i.e., weight, height, waist circumference, hip circumference, skinfolds, leptin) and methylation β-values at each CpG (measured by the Infinium MethylationEPIC BeadChip) were estimated among 391 singletons.
resultsTotal of 18% of mothers were obese (body mass index ≥ 30) and 27% centrally obese (waist-to-hip ratio ≥ 0.85). One Bonferroni significant CpG with respect to obesity (cg02975187) and two with central obesity (cg12053563, cg12549355) were identified (p < 6 × 10
conclusionWhile associations identified with multiple measures related to maternal adiposity suggest different pathways, methylation differences were small in magnitude.
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Registered trials
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