Evidence map›Paper›PMID 30618270›Full record

ArticleThe British journal of radiology2019

Value of CT iterative metal artifact reduction in PET/CT-clinical evaluation in 100 patients.

Christian Philipp Reinert, Christian la Fougère, Konstantin Nikolaou, Christina Pfannenberg, Sergios Gatidis

Abstract read
In one paragraph

Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian Philipp Reinert1 Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen , Tuebingen , Germany.
Christian la Fougère2 Department of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen , Tuebingen , Germany.
Konstantin Nikolaou1 Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen , Tuebingen , Germany.
Christina Pfannenberg1 Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen , Tuebingen , Germany.
Sergios Gatidis1 Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen , Tuebingen , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective: To assess the technical feasibility and diagnostic benefit of CT iterative metal artifact reduction (iMAR) in patients with metal implants undergoing positron emission tomography (PET/CT.

methods: PET/CTs of 100 patients with metal implants in different anatomical localization were retrospectively analyzed. CT data were reconstructed with iMAR and without iMAR (noMAR) and used in comparison for PET attenuation correction, generating iMAR-corrected and noMAR PET data. The effect of iMAR on quantitative CT and PET analysis was assessed by measurements of Hounsfield units (HUs) and standard uptake values (SUV) in predefined anatomical structures and pathological lesions in the vicinity of metal implants. Diagnostic confidence for lesion delineation was assessed using a 3-point scale.

results: For artifact-affected structures, mean HU of iMAR corrected CT significantly differed compared to noMAR CT and standard deviations were significantly lower [e.g. M. masseter: 71.01 ± 22.34 HU (iMAR) vs 98.89 ± 92.18 HU (noMAR), p < .01]. SUVs did not significantly differ in artifact-affected structures [e.g. M. masseter: SUVmean 0.96 ± 0.54 (iMAR) vs 0.97 ± 0.55 (noMAR); p > .89] and pathological findings [SUVmean 10.78 (iMAR) vs 10.81 (noMAR); p > .98] between iMAR and noMAR PET. Qualitatively, delineation was significantly improved in iMAR corrected CT for the interpretation of anatomical and pathological structures [e.g. score of pathologic lesions: 2.80 (iMAR) vs 2.31 (noMAR); p < .01].

conclusion: The use of iMAR in PET/CT significantly improves delineation of anatomical and pathological structures in the vicinity of metal implants in CT. PET quantification and PET image quality are not significantly affected by the use of iMAR-based attenuation correction independent of the presence of metal implants. ADVANCES IN KNOWLEDGE:: IMAR is a feasible algorithm in PET/CT improving CT image quality in the vicinity of metal implants without affecting PET quantification and can therefore be implemented in the clinical routine.

Indexed as

ArtifactsMetalsProstheses and ImplantsAdultAgedAged, 80 and overFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedPositron Emission Tomography Computed TomographyReproducibility of ResultsRetrospective StudiesTomography, X-Ray ComputedMetals

Identifiers

PMID30618270
PMCPMC6540858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.