ArticleJournal of pineal research2019
Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency.
Article in Journal of pineal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 72 citations in OpenAlex.
- ACSL4 in Alzheimer's disease: Pathogenetic mechanisms and potential therapeutic targets.Genes & diseases · 2026Review
- A GABAergic neural circuit from the suprachiasmatic nucleus to DG drives cognitive impairment in migraine mice.The journal of headache and pain · 2026Article
- Circadian Rhythms in Plasticity Markers Are Regulated by the Suprachiasmatic Nucleus and Local Circadian Oscillators in the Rodent Neocortex.Molecular neurobiology · 2025Article
- The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs.Molecules (Basel, Switzerland) · 2025Review
- A Pocket Guide for the Experimenter Studying Daily Rhythms in Memory-Related Behavior.Current protocols · 2025Article
- Light, Sound, and Melatonin: Investigating Multisensory Pathways for Visual Restoration.Medicina (Kaunas, Lithuania) · 2025Review
- The Melatonin Type 2 Receptor Agonist IIK7 Attenuates and Reverses Morphine Tolerance in Neuropathic Pain Rats Through the Suppression of Neuroinflammation in the Spinal Cord.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Melatonin: a ferroptosis inhibitor with potential therapeutic efficacy for the post-COVID-19 trajectory of accelerated brain aging and neurodegeneration.Molecular neurodegeneration · 2024Review
- α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway.Cellular and molecular life sciences : CMLS · 2024Article
- Targeting the circadian modulation: novel therapeutic approaches in the management of ASD.Frontiers in psychiatry · 2024Review
- Functional and pharmacological analyses of visual habituation learning in larval zebrafish.eLife · 2023Article
- Melatonin improves behavioral parameters and oxidative stress in zebrafish submitted to a leucine-induced MSUD protocol.Metabolic brain disease · 2023Article
- Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.Nutrients · 2022Article
- Light-Induced Functional Pinealectomy: Expression of MTBulletin of experimental biology and medicine · 2022Article
- Melatonin Alleviates Hyperglycemia-Induced Cardiomyocyte Apoptosis via Regulation of Long Non-Coding RNA H19/miR-29c/MAPK Axis in Diabetic Cardiomyopathy.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Microglia modulate hippocampal synaptic transmission and sleep duration along the light/dark cycle.Glia · 2022Article
- The Role of the Melatoninergic System in Circadian and Seasonal Rhythms-Insights From Different Mouse Strains.Frontiers in physiology · 2022Review
- Time of Day-Dependent Alteration of Hippocampal Rac1 Activation Regulates Contextual Fear Memory in Rats.Frontiers in molecular neuroscience · 2022Article
- Circadian rhythms as modulators of brain health during development and throughout aging.Frontiers in neural circuits · 2022Review
- Dysfunctional Learning and Verbal Memory in Patients with Elevated Tau Protein Levels and Serum Recoverin Autoantibodies-Case Series and Review.Brain sciences · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 4 countries.
Funding
Abstract
Mechanisms of hippocampus-related memory formation are time-of-day-dependent. While the circadian system and clock genes are related to timing of hippocampal mnemonic processes (acquisition, consolidation, and retrieval of long-term memory [LTM]) and long-term potentiation (LTP), little is known about temporal gating mechanisms. Here, the role of the neurohormone melatonin as a circadian time cue for hippocampal signaling and memory formation was investigated in C3H/He wildtype (WT) and melatonin receptor-knockout (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.