Evidence map›Paper›PMID 30617868›Full record

Observational studyAnnals of surgical oncology2019

Psychosocial Risks are Independently Associated with Cancer Surgery Outcomes in Medically Comorbid Patients.

Ira L Leeds, Patrick M Meyers, Zachary O Enumah, Jin He, Richard A Burkhart, Elliott R Haut, Jonathan E Efron, Fabian M Johnston

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Annals of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ira L LeedsDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Patrick M MeyersDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Zachary O EnumahDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jin HeDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Richard A BurkhartDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Elliott R HautDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jonathan E EfronDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Fabian M JohnstonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. fjohnst4@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Clinical and Laboratory Research Training for Surgical OncologistsT32CA126607 · NCI · JOHNS HOPKINS UNIVERSITY · PI CAMERON, ANDREW M. · 2008 to 2024
$6.0M
Promoting Early Utilization of Palliative Care for African Americans Using Culturally Informed Patient NavigationK08HS024736 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI JOHNSTON, FABIAN M · 2016 to 2020
$738k
Agency for Healthcare Research and Quality 1K08HS024736AHRQ HHS K08 HS024736American Society of Colon and Rectal Surgeons GSRRIG-031NCI NIH HHS 5T32CA126607NCI NIH HHS L30 CA220744NCI NIH HHS T32 CA126607
6 · The paper itself

Abstract

backgroundThe specific effect of psychosocial risk factors on surgical outcomes in cancer patients remains unexplored. The purpose of this prospective observational study was to assess the association of preoperative psychosocial risk factors and 30-day complications following cancer surgery.

methodsPsychosocial risks among elective gastrointestinal cancer surgery patients were ascertained through structured interviews using well-established screening forms. We then collected postoperative course by chart review. Multivariable analysis of short-term surgical outcomes was performed in those with a low versus high number of psychosocial risks.

resultsOverall, 142 patients had a median age of 65 years (interquartile range 55-71), 55.9% were male, and 23.1% were non-White. More than half (58.2%) of the study population underwent a resection for a hepato-pancreato-biliary primary tumor, and 31.9% had a colorectal primary tumor. High-risk biomedical comorbidities were present in 43.5% of patients, and three-quarters of patients (73.4%) had at least one psychosocial risk. Complication rates in patients with at least one psychosocial risk were 28.0 absolute percentage points higher than those with no psychosocial risks (54.4% vs. 26.2%, p = 0.039). Multiple psychosocial risk factors in medically comorbid patients independently conferred an increase in the odds of a complication by 3.37-fold (95% CI 1.08-10.48, p = 0.036) compared with those who had one or no psychosocial risks.

conclusionsWe demonstrated a more than threefold odds of a complication in medically comorbid patients with multiple psychosocial risks. These findings support the use of psychosocial risks in preoperative assessment and consideration for inclusion in preoperative optimization efforts.

Indexed as

AgedComorbidityElective Surgical ProceduresFemaleFollow-Up StudiesGastrointestinal NeoplasmsHumansMaleMiddle AgedPostoperative ComplicationsPrognosisProspective StudiesRisk FactorsStress, Psychological

Identifiers

PMID30617868
PMCPMC8710142
OpenAlexW2909197587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.