Evidence map›Paper›PMID 30617611›Full record

ArticleAnnals of intensive care2019

Low-flow CO

Jens Nentwich, Dominic Wichmann, Stefan Kluge, Simone Lindau, Haitham Mutlak, Stefan John

Open access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Effects of extracorporeal COCritical care (London, England) · 2024
    Pooled it
  2. Pooled it
  3. Extracorporeal COAnnals of intensive care · 2026
    Article
  4. Article
  5. Effect of low bicarbonate substitution solution on COIntensive care medicine experimental · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Modeling acid-base balance during continuous kidney replacement therapy.Journal of clinical monitoring and computing · 2022
    Article
  12. Observational
  13. Review
  14. Extracorporeal COSeminars in dialysis · 2021
    Article
  15. The use of extracorporeal COAnnals of intensive care · 2021
    Review
  16. Review
  17. Options in extracorporeal support of multiple organ failure.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020
    Review
  18. Low-flow assessment of current ECMO/ECCOCritical care (London, England) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Jens NentwichMedical Intensive Care, Department of Cardiology, Klinikum Nuremberg, Paracelsus Medical University, Nuremberg, Germany.
Dominic WichmannDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Stefan KlugeDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Simone LindauDepartment of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany.
Haitham MutlakDepartment of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany.
Stefan JohnMedical Intensive Care, Department of Cardiology, Klinikum Nuremberg, Paracelsus Medical University, Nuremberg, Germany. stefan.john@klinikum-nuernberg.de.
Nuremberg Hospital · DEGoethe University Frankfurt · DEUniversität Hamburg · DEUniversity Hospital Frankfurt · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

Baxter Healthcare Corporation unknown
6 · The paper itself

Abstract

backgroundLung-protective strategies are the cornerstone of mechanical ventilation in critically ill patients with both ARDS and other disorders. Extracorporeal CO

methodsTwenty patients were treated with the combined system which incorporates a membrane lung (0.32 m

resultsThe system delivered ECCO

conclusionsThe investigated low-flow ECCO

Indexed as

Acute kidney injuryLow-flow extracorporeal CO2 removalLung protectionMechanical ventilationMulti-organ supportRenal replacement therapyVentilator-induced lung injury

Identifiers

PMID30617611
PMCPMC6323065
OpenAlexW2910554837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.