Evidence map›Paper›PMID 30617563›Full record

ArticleEJNMMI research2019

A phase 1, first-in-human study of

Sun Young Chae, Tae-Won Kwon, Soyoung Jin, Sun U Kwon, Changhwan Sung, Seung Jun Oh, Sang Ju Lee, Jungsu S Oh, Youngjin Han, Yong-Pil Cho and 6 more

4 registry-linked trialsAbstract read
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02864810 phase1completednot on this map

A Phase 1, Open-label, Non-randomized, Single Center Study to Assess Safety, Pharmacokinetics, Biodistribution, Internal Radiation Dosimetry and Diagnostic Performance of [18F]GP1 Positron Emission Tomography in Subjects With Venous or Arterial Thromboembolism

TypeinterventionalSponsorAsan FoundationRan2016 to 2017Enrolled32ConditionsThromboembolismArms[18F]GP1
NCT04073875 completednot on this map

18F-GP1 Positron Emission Tomography-computed Tomography to Detect Bioprosthetic Aortic Valve Thrombosis; the Biothrombus Study.

TypeobservationalSponsorUniversity of EdinburghRan2019 to 2021Enrolled53ConditionsThrombosis Cardiac, Aortic Valve DiseaseArms18F-GP1
NCT04156230 phase2completednot on this mapstarted 2020, after this paper: background citation

A Phase 2, Open-label, Non-randomized, Single Center Study to Assess Diagnostic Validity of [18F]GP1 Positron Emission Tomography/Computed Tomography for Acute Deep Vein Thrombosis of the Lower Extremities in Symptomatic Patients

TypeinterventionalSponsorDae Hyuk MoonRan2020 to 2025Enrolled52ConditionsVenous ThrombosisArms[18F]GP1 positron emission tomography/computed tomography
NCT05636748 recruitingnot on this mapstarted 2023, after this paper: background citation

The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke

TypeobservationalSponsorUniversity of EdinburghRan2023 to 2026Enrolled120ConditionsStroke, PET, ThrombosisArms18F-GP1 PET/CT, Agitated Contrast Echocardiogram, MRI Head, ECG Monitoring
3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Latest Advances in Multimodality Imaging of Aortic Stenosis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Review
  8. Article
  9. Review
  10. Non-invasive Multimodality Imaging of Coronary Vulnerable Patient.Frontiers in cardiovascular medicine · 2022
    Review
  11. Review
  12. Review
  13. American journal of respiratory and critical care medicine · 2021
    Article
  14. KSNM60 in Cardiology: Regrowth After a Long Pause.Nuclear medicine and molecular imaging · 2021
    Review
  15. GMP-Compliant Radiosynthesis of [Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sun Young ChaeDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Tae-Won KwonDepartment of Vascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Soyoung JinDepartment of Nuclear Medicine, Nowon Eulji Medical Center, Eulji University, Seoul, Republic of Korea.
Sun U KwonDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Changhwan SungDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Seung Jun OhDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Sang Ju LeeDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Jungsu S OhDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Youngjin HanDepartment of Vascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Yong-Pil ChoDepartment of Vascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Narae LeeDepartment of Nuclear Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Ji Young KimDepartment of Nuclear Medicine, Guri Hospital of Hanyang University Medical Center, Hanyang University College of Medicine, Seoul, Republic of Korea.
Norman KoglinLife Molecular Imaging GmbH (formerly Piramal Imaging GmbH), Berlin, Germany.
Mathias BerndtLife Molecular Imaging GmbH (formerly Piramal Imaging GmbH), Berlin, Germany.
Andrew W StephensLife Molecular Imaging GmbH (formerly Piramal Imaging GmbH), Berlin, Germany.
Dae Hyuk MoonDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. dhmoon@amc.seoul.kr.ORCID https://orcid.org/0000-0001-9892-4276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsAdult patients who had signs or symptoms of AAT or had recently undergone arterial intervention or surgery within 14 days prior to

resultsAmong the ten eligible patients assessed, underlying diseases were abdominal aortic aneurysm with endovascular repair (n = 6), bypass surgery and stent placement (n = 1), endarterectomy (n = 1), arterial dissection (n = 1) and acute cerebral infarction (n = 1).

conclusions

trial registrationClinicalTrials.gov identifier: NCT02864810 , Registered August 3, 2016.

Indexed as

18F-GP1Arterial thrombosisGlycoprotein IIb/IIIa receptorPlatelet activationPositron emission tomography

Identifiers

PMID30617563
PMCPMC6323046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.