Evidence map›Paper›PMID 30617487›Full record

ArticleEuropean radiology2019

Second-generation motion correction algorithm improves diagnostic accuracy of single-beat coronary CT angiography in patients with increased heart rate.

Junfu Liang, Ying Sun, Ziqing Ye, Yanchun Sun, Lei Xu, Zhen Zhou, Brian Thomsen, Jianying Li, Zhonghua Sun, Zhanming Fan

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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  12. Cardiac Computed Tomography: Technological Developments and Clinical Applications.Journal of cardiovascular development and disease · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Junfu LiangDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd., Chaoyang District, Beijing, 100029, China.
Ying SunDepartment of Radiology, Beijing Huairou Hospital, No. 9 Yongtai North Street, Huairou District, Beijing, 101400, China.
Ziqing YeDepartment of Radiology, Beijing Huairou Hospital, No. 9 Yongtai North Street, Huairou District, Beijing, 101400, China.
Yanchun SunDepartment of Radiology, Beijing Huairou Hospital, No. 9 Yongtai North Street, Huairou District, Beijing, 101400, China.
Lei XuDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd., Chaoyang District, Beijing, 100029, China. leixu2001@hotmail.com.
Zhen ZhouDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd., Chaoyang District, Beijing, 100029, China.
Brian ThomsenGE Healthcare, Milwaukee, WI, USA.
Jianying LiCT Laboratory, GE Healthcare China, Beijing, China.
Zhonghua SunDepartment of Medical Radiation Sciences, Curtin University, Perth, WA, 6845, Australia.
Zhanming FanDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd., Chaoyang District, Beijing, 100029, China.
Beijing Anzhen Hospital · CNCapital Medical University · CNCurtin University · AUWheaton Franciscan Healthcare · US

Funding

National Key R&D Program of China 2016YFC1300300The National Natural Science Foundation of China 81641069
6 · The paper itself

Abstract

objectiveTo assess the effect of a second-generation motion correction algorithm on the diagnostic accuracy of coronary computed tomography angiography (CCTA) using a 256-detector row CT in patients with increased heart rates.

methodsEighty-one consecutive symptomatic cardiac patients with increased heart rates (≥ 75 beats per min) were enrolled. All patients underwent CCTA and invasive coronary angiography (ICA). CCTA was performed with a 256-detector row CT using prospectively ECG-triggered single-beat protocol. Images were reconstructed using standard (STD) algorithm, first-generation intra-cycle motion correction (MC1) algorithm, and second-generation intra-cycle motion correction (MC2) algorithm. The image quality of coronary artery segments was assessed by two experienced radiologists using a 4-point scale (1: non-diagnostic and 4: excellent), according to the 18-segment model. Diagnostic performance for segments with significant lumen stenosis (≥ 50%) was compared between STD, MC1, and MC2 by using ICA as the reference standard.

resultsThe mean effective dose of CCTA was 1.0 mSv. On per-segment level, the overall image quality score and interpretability were improved to 3.56 ± 0.63 and 99.2% due to the use of MC2, as compared to 2.81 ± 0.85 and 92.5% with STD and 3.21 ± 0.79 and 97.2% with MC1. On per-segment level, compared to STD and MC1, MC2 improved the sensitivity (92.2% vs. 79.2%, 80.7%), specificity (97.8% vs. 82.1%, 90.8%), positive predictive value (89.9% vs. 48.4%, 65.1%), negative predictive value (98.3% vs. 94.9%, 95.7%), and diagnostic accuracy (96.8% vs. 81.5%, 89.0%).

conclusionA second-generation intra-cycle motion correction algorithm for single-beat CCTA significantly improves image quality and diagnostic accuracy in patients with increased heart rate. KEY POINTS: • A second-generation motion correction (MC2) algorithm can further improve the image quality of all coronary arteries than a first-generation motion correction (MC1). • MC2 algorithm can significantly reduce the number of false positive segments compared to standard and MC1 algorithm.

Indexed as

AdultAgedAlgorithmsArrhythmias, CardiacComputed Tomography AngiographyCoronary AngiographyCoronary VesselsFemaleHeart RateHumansMaleMiddle AgedMotionRadiation DosageSensitivity and SpecificityCoronary angiographyCoronary vesselsHeart rateMotionTomography, X-ray computed

Identifiers

PMID30617487
OpenAlexW2910813723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.