Trial reportSaudi medical journal2019
Is prilocaine safe and potent enough for use in the oral surgery of medically compromised patients.
Trial report in Saudi medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Rules of selection for a safe local anesthetic in dentistry.Journal of Taibah University Medical Sciences · 2023Article
- A new cause of the adrenal crisis in dental and medical patients: Opioid-induced adrenal insufficiency.Journal of Taibah University Medical Sciences · 2023Article
- Comparison of the Anaesthesia Success Rate in Maxillary First and Second Molars with 3% Prilocaine as the Anaesthetic Agent.European endodontic journal · 2021Article
- Local anesthesia in oral and maxillofacial surgery: A review of current opinion.Journal of dental sciences · 2021Review
- Measuring the Level of Medical-Emergency-Related Knowledge among Senior Dental Students and Clinical Trainers.International journal of environmental research and public health · 2021Article
- Management of an emergency tooth extraction in diabetic patients on the dental chair.The Saudi dental journal · 2020Review
- Selection of the safest local anesthetic for dental treatment in medically compromised patients: A comprehensive review.Saudi journal of anaesthesiaReview
- How Successful is Supplemental Intraseptal and Buccal Infiltration Anaesthesia in the Mandibular Molars of Patients Undergoing Root Canal Treatment or Tooth Extraction?Journal of oral & maxillofacial researchArticle
- Does articaine, rather than prilocaine, increase the success rate of anaesthesia for extraction of maxillary teeth.Saudi journal of anaesthesiaArticle
- Indian Society of Periodontology Good Clinical Practice Recommendations for dental pain management and use of analgesics.Journal of Indian Society of PeriodontologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the potency and speed of action of 2% lidocaine and 3% prilocaine for upper teeth extractions.
methodsThis prospective clinical study was conducted from November 2016 to May 2017. Ninety-six patients, aged between 16 to 70 years old were recruited in this study. Two regimens were randomly administered over one visit. Patients, treatment group I, received 2% lidocaine with 1:00.000 adrenaline. Patients treatment group II received prilocaine 3% and felypressin 0.03 I.U. per ml. The efficacy of pulp anesthesia was determined by electronic pulp testing. At any point of trial (10 minutes), the anesthetized tooth becomes unresponsive for maximal pulp stimulation (64 reading), the extraction was carried out. Results: There were no significant differences in the mean onset time of pulpal anesthesia and extraction between the prilocaine and lidocaine buccal infiltration groups (p=0.28). However, clinically, the patients in prilocaine group recorded faster onset time of anesthesia and teeth extraction than those in lidocaine group. Conclusion: Prilocaine has a better clinical performance in terms of providing rapid dental anesthesia and earlier teeth extraction than lidocaine but the differences were not significant. Prilocaine with felypressin could be a good choice for patients who have contraindication to the use of lidocaine with adrenaline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.