ArticleNature microbiology2019
Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis.
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Article in Nature microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Serum interleukin-10 levels and mortality in severe fever with thrombocytopenia syndrome: a systematic review and meta-analysis.Frontiers in immunology · 2026Pooled it
- Interplay between SFTSV and host innate immunity: Viral evasion mechanisms, pathogenesis, and therapeutic perspectives.iScience · 2026Review
- Comparison of the pathogenicity in type I interferon receptor deficient A129 mice and characterization of amino acid substitutions among severe fever with thrombocytopenia syndrome virus strains.The Journal of veterinary medical science · 2026Article
- SFTSV NSs protein is a tick antiviral RNAi response suppressor.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Unraveling the complexities: A comprehensive review of severe fever with thrombocytopenia syndrome and its associated complications.iScience · 2026Review
- The ASFV CD2v protein inhibits apoptosis by inducing proteasomal degradation of BimJournal of virology · 2026Article
- Article
- Recombinant Dabie bandavirus as a bivalent vaccine platform inducing protective immunity against intracellular pathogens and cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Secondary fungal infections in severe acute viral diseases: clinical features and underlying immune mechanisms.Frontiers in microbiology · 2026Review
- Integration of SFTSV Viral Load, Age, and Double-Negative B-Cells as Prognostic Biomarkers for Severe Fever With Thrombocytopenia Syndrome Outcomes.Journal of immunology research · 2026Article
- Research progress on antiviral drugs and vaccines for severe fever with thrombocytopenia syndrome.Frontiers in immunology · 2026Review
- Review
- NSs: the multifaceted bunyavirus virulence factor.Npj viruses · 2025Review
- Interferon-stimulated gene screening identifies CCND3 as a host restriction factor against emerging high-pathogenic bandaviruses.Nature communications · 2025Article
- The non-structural protein of SFTSV activates NLRP1 and CARD8 inflammasome through disrupting the DPP9-mediated ternary complex.PLoS pathogens · 2025Article
- A viral necrosome mediates direct RIPK3 activation to promote inflammatory necroptosis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- SFTSV NSs interacts with AGO2 to regulate the RNAi pathway for viral replication.Journal of virology · 2025Article
- Latest advances and prospects in the pathogenesis, animal models, and vaccine research of severe fever with thrombocytopenia syndrome virus.Frontiers in immunology · 2025Review
- Advancements in vaccine development and therapeutic approaches for severe fever with Thrombocytopenia Syndrome.Frontiers in cellular and infection microbiology · 2025Review
- Review
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 4 countries.
Younho ChoiDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA.
Su-Jin ParkDepartment of Microbiology and Zoonotic Infectious Diseases Research Center, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, South Korea.
Yinyan SunNational Institute of Biological Sciences, Beijing, ZGC Life Science Park, Changping, Beijing, China.
Ji-Seung YooDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA.
Raghavendra Sumanth PudupakamDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1610-0474
Suan-Sin FooDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA.
Woo-Jin ShinDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-0218-2058
Sally B ChenDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA.
Philip N TsichlisMolecular Oncology Research Institute, Tuft Medical School, Boston, MA, USA.
Won-Ja LeeDivision of Arboviruses, National Research Institute of Health, Korea Centers for Disease Control and Prevention, Cheongju, South Korea.
Jong-Soo LeeCollege of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
Wenhui LiNational Institute of Biological Sciences, Beijing, ZGC Life Science Park, Changping, Beijing, China.
Benjamin BrennanMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0003-4707-726X
Young-Ki ChoiDepartment of Microbiology and Zoonotic Infectious Diseases Research Center, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, South Korea.ORCID http://orcid.org/0000-0002-0872-0147
Jae U JungDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Zilkha Neurogenetic Institute, Los Angeles, CA, USA. jaeujung@med.usc.edu.ORCID http://orcid.org/0000-0003-4559-8774
University of Southern California · USNational Institute of Biological Sciences, Beijing · CNChungbuk National University · KRChungnam National University · KRKorea Disease Control and Prevention Agency · KRMolecular Oncology (United States) · USMRC University of Glasgow Centre for Virus Research · GB
Funding
Roles of the K3 and K5 in KSHV Persistence and PathogenesisP01CA180779 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2013 to 2017
$7.3MMolecular Basis of KSHV oncogenesisR35CA200422 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2016 to 2022
$6.1MRole of viral BCI-2 mediated anti-apoptosis and-autophagyR01AI073099 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2007 to 2017
$4.3MKSHV Epigenetic RegulationR01DE023926 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2013 to 2024
$4.2MSFTSV nonstructural protein NSs-mediated immunopathogenesisR01AI140705 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2018 to 2022
$4.2MGenetic evolution, pathogenesis and immune responses in mother to child transmission of ZIKVR01AI140718 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHENG, GENHONG, JUNG, JAE U · 2018 to 2022
$3.8MTRIM9-mediated anti-viral immune pathwayR01AI116585 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OU, J.-H. JAMES · 2015 to 2019
$2.3MRole of autophagy for Zika virus lifecycleR21AI129496 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2017 to 2018
$454kRegulation of lymphangiogenesis by KSHV vIRF3R21DE027888 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2018 to 2019
$451kMedical Research Council MC_UU_12014/8NCI NIH HHS P01 CA180779NCI NIH HHS R35 CA200422NIAID NIH HHS R01 AI073099NIAID NIH HHS R01 AI116585NIAID NIH HHS R01 AI140705NIAID NIH HHS R01 AI140718NIAID NIH HHS R21 AI129496NIDCR NIH HHS R01 DE023926NIDCR NIH HHS R21 DE027888Wellcome Trust 210462/Z/18/Z
Abstract
Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV), listed in the World Health Organization Prioritized Pathogens, is an emerging phlebovirus with a high fatality
Indexed as
Host-Pathogen InteractionsSignal TransductionAdaptor Proteins, Signal TransducingAnimalsBunyaviridae InfectionsFemaleHEK293 CellsHeLa CellsHumansInterleukin-10MaleMAP Kinase Kinase KinasesMiceMice, 129 StrainMice, Inbred BALB CMice, Inbred C57BLAdaptor Proteins, Signal TransducingInterleukin-10Map3k8 protein, mouseMAP Kinase Kinase KinasesProto-Oncogene ProteinsTnip2 protein, mouseViral Nonstructural Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.