Evidence map›Paper›PMID 30617222›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

IRAK-M Associates with Susceptibility to Adult-Onset Asthma and Promotes Chronic Airway Inflammation.

Yi Liu, Mingqiang Zhang, Lili Lou, Lun Li, Youming Zhang, Wei Chen, Weixun Zhou, Yan Bai, Jinming Gao

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Yi LiuDepartment of Respiratory Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Mingqiang ZhangDepartment of Respiratory Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Lili LouDepartment of Respiratory Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Lun LiDepartment of Respiratory Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.ORCID 0000-0001-6226-1773
Youming ZhangGenomics Medicine Section, National Heart and Lung Institute, Imperial College London, London SW3 6LY, United Kingdom.ORCID 0000-0001-5403-4044
Wei ChenDepartment of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Weixun ZhouDepartment of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China; and.ORCID 0000-0002-7459-7343
Yan BaiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-8393-3062
Jinming GaoDepartment of Respiratory Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China; gjinming@yahoo.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNBrigham and Women's Hospital · USLung Institute · US

Funding

Cholinergic hyperinnernation in early life regulates long-term airway reactivityK08HL135443 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BAI, YAN · 2017 to 2021
$861k
NHLBI NIH HHS K08 HL135443
6 · The paper itself

Abstract

IL-1R-associated kinase (IRAK)-M regulates lung immunity during asthmatic airway inflammation. However, the regulatory effect of IRAK-M differs when airway inflammation persists. A positive association between

Indexed as

AdultAnimalsAsthmaChinaCohort StudiesDendritic CellsDisease Models, AnimalFemaleGenetic Predisposition to DiseaseHumansInflammationInterleukin-1 Receptor-Associated KinasesLungMaleMiceMice, Inbred C57BLInterleukin-1 Receptor-Associated KinasesIRAK3 protein, humanIrak3 protein, mouse

Identifiers

PMID30617222
PMCPMC6344301
OpenAlexW2907156561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.