Evidence map›Paper›PMID 30617116›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2019

The Multifaceted B Cell Response to Influenza Virus.

Jonathan H Lam, Nicole Baumgarth

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Immune Responses to Influenza Infection in Children.Open forum infectious diseases · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. EZH2 coordinates memory B-cell programming and recall responses.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jonathan H LamCenter for Comparative Medicine, University of California, Davis, Davis, CA 95616.ORCID 0000-0002-2811-7177
Nicole BaumgarthCenter for Comparative Medicine, University of California, Davis, Davis, CA 95616; nbaumgarth@ucdavis.edu.ORCID 0000-0002-2891-4483
University of California, Davis · US

Funding

Virus-induced Cell Fate Decisions in Anti-Viral ImmunityU19AI109962 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEE, FRANCES EUN-HYUNG · 2014 to 2018
$11.6M
TRAINING IN COMPARATIVE LUNG BIOLOGY AND MEDICINET32HL007013 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI Elena Goncharova, Nicholas J. KENYON · 1985 to 2026
$10.1M
Protective humoral immunity to influenza infectionR01AI117890 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BAUMGARTH, NICOLE · 2016 to 2020
$2.4M
NHLBI NIH HHS T32 HL007013NIAID NIH HHS R01 AI117890NIAID NIH HHS U19 AI109962
6 · The paper itself

Abstract

Protection from yearly recurring, highly acute infections with a pathogen that rapidly and continuously evades previously induced protective neutralizing Abs, as seen during seasonal influenza virus infections, can be expected to require a B cell response that is too highly variable, able to adapt rapidly, and able to reduce morbidity and death when sterile immunity cannot be garnered quickly enough. As we outline in this

Indexed as

AnimalsAntibodies, ViralAntigenic VariationAntigens, ViralB-LymphocytesCross ProtectionHumansImmunity, HeterologousImmunity, HumoralImmunity, InnateInfluenza A virusInfluenza, HumanInfluenza VaccinesOrthomyxoviridae InfectionsAntibodies, ViralAntigens, ViralInfluenza Vaccines

Identifiers

PMID30617116
PMCPMC6327962
OpenAlexW2910760765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.