Evidence map›Paper›PMID 30617062›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Chronic and acute stress monitoring by electrophysiological signals from adrenal gland.

Sung Hyuk Sunwoo, Ju Seung Lee, SungJun Bae, Yiel Jae Shin, Chang Seong Kim, Soo Yeon Joo, Hong Sang Choi, Minah Suh, Soo Wan Kim, Young Jin Choi and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sung Hyuk SunwooCenter for Neuroscience Imaging Research, Institute of Basic Science, 16419 Suwon, Korea.
Ju Seung LeeSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 16419 Suwon, Korea.
SungJun BaeCenter for Neuroscience Imaging Research, Institute of Basic Science, 16419 Suwon, Korea.
Yiel Jae ShinSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 16419 Suwon, Korea.
Chang Seong KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Soo Yeon JooDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Hong Sang ChoiDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Minah SuhCenter for Neuroscience Imaging Research, Institute of Basic Science, 16419 Suwon, Korea.
Soo Wan KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Young Jin ChoiDepartment of Nanotechnology and Advanced Materials Engineering, Sejong University, 05006 Seoul, Korea jini38@sejong.ac.kr taeilkim@skku.edu.
Tae-Il KimDepartment of Biomedical Engineering, Sungkyunkwan University (SKKU), 16419 Suwon, Korea; jini38@sejong.ac.kr taeilkim@skku.edu.ORCID 0000-0002-6667-5356
Chonnam National University · KRInstitute for Basic Science · KRSungkyunkwan University · KRSejong University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present electrophysiological (EP) signals correlated with cellular cell activities in the adrenal cortex and medulla using an adrenal gland implantable flexible EP probe. With such a probe, we could observe the EP signals from the adrenal cortex and medulla in response to various stress stimuli, such as enhanced hormone activity with adrenocorticotropic hormone, a biomarker for chronic stress response, and an actual stress environment, like a forced swimming test. This technique could be useful to continuously monitor the elevation of cortisol level, a useful indicator of chronic stress that potentially causes various diseases.

Indexed as

Adrenal CortexAdrenal GlandsAdrenocorticotropic HormoneAnimalsElectrophysiological PhenomenaMaleMedulla OblongataRatsStress, PhysiologicalAdrenocorticotropic Hormonebioimplantbiosensorcortisolelectrophysiologystress

Identifiers

PMID30617062
PMCPMC6347678
OpenAlexW2910938101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.