Evidence map›Paper›PMID 30617055›Full record

ArticleBioscience reports2019

Association of matrix Gla protein polymorphism and knee osteoarthritis in a chinese population.

Wenpeng Hui, Zhong Cao, Xiao Wang, Junfeng Zhu

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wenpeng HuiDepartment of Spinal Surgery, Shandong Provincial Western Hospital, 4 Duanxing West Road, Jinan, Shandong, China.
Zhong CaoDepartment of Spinal Surgery, Shandong Provincial Western Hospital, 4 Duanxing West Road, Jinan, Shandong, China.
Xiao WangDepartment of Spinal Surgery, Shandong Provincial Western Hospital, 4 Duanxing West Road, Jinan, Shandong, China.
Junfeng ZhuDepartment of Orthopedic, Suichang People's hospital, 143 Miaogao North Street, Suichang, Lishui, Zhejiang, China junfengzhu5566@126.com.ORCID 0000-0002-4445-3883
Shandong Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have explored the association between matrix Gla protein (MGP) gene polymorphism and knee osteoarthritis (OA) risk; however, they obtained conflicting findings. The present study aims to explore the association of MGP gene polymorphism and OA risk in a Chinese Han population. A total of 256 patients with radiographic knee OA and 327 control subjects were recruited in this case-control study. The genotypes of MGP gene rs1800802 polymorphism was determined by standard PCR and restriction fragment length polymorphism (PCR-RLFP). In this case-control study, we observed that MGP gene rs1800802 polymorphism increased the risk of knee OA. Subgroup analyses also found that rs1800802 polymorphism was related to the elevated risk for knee OA among the female, smoker, drinker, and body mass index (BMI) ≥25 kg/m

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseAdultAgedAsian PeopleBody Mass IndexCalcium-Binding ProteinsExtracellular Matrix ProteinsFemaleGenotypeHumansMaleMatrix Gla ProteinMiddle AgedOsteoarthritis, KneePolymorphism, Single NucleotideCalcium-Binding ProteinsExtracellular Matrix ProteinsMatrix Gla ProteinMGPOsteoarthritisPolymorphismsingle nucleotide polymorphisms

Identifiers

PMID30617055
PMCPMC6350040
OpenAlexW2910643394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.