ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2019
Caregiver-Care Recipient Relationship Closeness is Associated With Neuropsychiatric Symptoms in Dementia.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Digital Reminiscence for Predeath Grief Among Family Caregivers of Patients With Dementia: A Pilot Randomized Clinical Trial.JAMA network open · 2026Trial
- Caregiver- and Care Recipient-Related Factors Linked to Pain in Family Caregivers of Persons Living with Dementia.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Associations between sensory impairment and neuropsychiatric symptoms among older adults: a moderated mediating model.BMC public health · 2026Article
- Diminished preparatory physiological responses in people with dementia: associations with caregiver health and relationship quality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- The Relationship of Alzheimer's Disease and Related Dementias Blood-Based Biomarkers and Informant-Reported Neuropsychiatric Symptoms Differs by Informant Type in Older Adults Without Dementia.International journal of geriatric psychiatry · 2025Article
- Caregivers' Perspectives on Discussions of Medical Treatment Preferences for People Living With Dementia Are Associated With Their Dementia Health Literacy and the Caregiving Relationship.The Gerontologist · 2025Article
- Expressed emotion mediates the association between caregiver relationship closeness and psychological symptoms in people with dementia.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025Article
- Sleep quality differences among caregivers for persons living with and without dementia.Aging & mental health · 2024Article
- Characteristics of Informal Caregivers and Social Participation of People With Dementia.The Gerontologist · 2024Article
- Addressing relationship quality of people with dementia and their family carers: which profiles require most support?Frontiers in psychiatry · 2024Article
- Malnutrition and neuropsychiatric symptoms in dementia: the Cache County Dementia Progression Study.International psychogeriatrics · 2023Observational
- Association between prevalence rate of dementia with Lewy bodies and sleep characteristics in Chinese old adults.Frontiers in human neuroscience · 2022Article
- E-mail-based health care in patients with dementia during the pandemic.Frontiers in psychiatry · 2022Article
- Caregiver "objective attitude" toward patients with neurodegenerative disease: Consequences for caregiver strain and relationship closeness.Aging & mental health · 2021Article
- Caregiving burnout of community-dwelling people with dementia in Hong Kong and New Zealand: a cross-sectional study.BMC geriatrics · 2021Article
- Caregiving Factors as Predictors of Care Recipient Mortality.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021Article
- Recruitment and retention of participant and study partner dyads in two multinational Alzheimer's disease registration trials.Alzheimer's research & therapy · 2021Article
- A Narrative Review Examining the Utility of Interpersonal Synchrony for the Caregiver-Care Recipient Relationship in Alzheimer's Disease and Related Dementias.Frontiers in psychology · 2021Review
- The Impact of the COVID-19 Pandemic on Alzheimer's Disease and Other Dementias.Frontiers in psychiatry · 2021Article
- Benefits, Challenges and Solutions for Implementing Personalised Music Playlist Programs in Residential Aged Care in Australia.Journal of multidisciplinary healthcare · 2021Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveCloser caregiver-care recipient (CG-CR) relationships are associated with better cognitive and functional abilities, activities of daily living (in persons with dementia), and lower informal care costs.
methodsDue to the difficulty in treating neuropsychiatric symptoms (NPSs) and their detrimental effects on caregivers and care recipients, we examined whether closeness of CG-CR relationships was associated with overall NPS severity or with specific NPS symptom domains in care recipients. In a longitudinal population-based study in Cache County, Utah, the 12-item Neuropsychiatric Inventory (NPI-12) was assessed in 300 CG-CR dyads. Caregivers reported current relationship closeness using the Whitlatch Relationship Closeness Scale. Linear mixed models examined associations between CG-CR closeness and NPI-12 total score or selected symptom domains over time (observation period: 2002-2012).
resultsIn unadjusted linear mixed models, higher closeness scores were associated with a five-point lower NPI-12 score and a one-point lesser increase in NPI-12 per year. NPI scores also showed lower affective cluster scores (two points) and lesser increase in psychosis cluster (approximately 0.5 points per year) and agitation/aggression (0.16 points per year) for each unit increase in closeness. When controlling for NPI caregiver distress, associations between closeness and NPSs diminished to a 0.5-point lesser increase in total NPI-12 score per year. Adjusted models for NPI domains/clusters showed -0.32 points per year for the psychosis cluster, -0.11 points per year for agitation/aggression, and -0.67 overall for the affective cluster.
conclusionHigher CG-CR closeness, a potentially modifiable factor, is associated with lower NPS severity and may provide a target for intervention.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.