ArticleeLife2019
A β-carotene-binding protein carrying a red pigment regulates body-color transition between green and black in locusts.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- A systematic review of locust phase polyphenism: from proximate mechanisms to ecology and management.PeerJ · 2026Pooled it
- Genomic and Morphological Insights Into the Adaptive Evolution of Honeybees in Rocky Desertification Habitats.Ecology and evolution · 2026Article
- The Integrative Imperatives of Locust Phase Polyphenism Research: A Bibliometric Analysis.Integrative organismal biology (Oxford, England) · 2026Review
- Replicated Differential Expression Analysis in a Green-Brown Polymorphic Grasshopper Reveals Role of Beta-Carotene-Binding Protein in Body Coloration.Molecular ecology · 2025Article
- Host-Affected Body Coloration Dynamics inInsects · 2025Article
- The pigment transporter Redboy confers programmed body colour transition in orchid mantises.Nature ecology & evolution · 2025Article
- Molecular basis governing diapause and pigmentation in the hawthorn spider mite, Amphitetranychus viennensis.BMC biology · 2025Article
- Parental experiences orchestrate locust egg hatching synchrony by regulating nuclear export of precursor miRNA.Nature communications · 2024Article
- Insights into the molecular mechanism of yellow cuticle coloration by a chitin-binding carotenoprotein in gregarious locusts.Communications biology · 2024Article
- Transcriptomics Provide Insights into the Photoperiodic Regulation of Reproductive Diapause in the Green Lacewing,Insects · 2024Article
- Uridine Diphosphate Glycosyltransferases (UGTs) Involved in the Carotenoid-Based Body Color Difference betweenInsects · 2023Article
- Spatially differential regulation of ATF2 phosphorylation contributes to warning coloration of gregarious locusts.Science advances · 2023Article
- PLIN2-induced ectopic lipid accumulation promotes muscle ageing in gregarious locusts.Nature ecology & evolution · 2023Article
- Cytosolic and mitochondrial ribosomal proteins mediate the locust phase transition via divergence of translational profiles.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Multi-Omics Reveals the Effect of Population Density on the Phenotype, Transcriptome and Metabolome ofInsects · 2023Article
- Glutamate-GABA imbalance mediated by miR-8-5p and its STTM regulates phase-related behavior of locusts.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Piwi/piRNAs control food intake by promoting neuropeptide F expression in locusts.EMBO reports · 2022Article
- Locust density shapes energy metabolism and oxidative stress resulting in divergence of flight traits.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Comparative analysis of phenotypic plasticity sheds light on the evolution and molecular underpinnings of locust phase polyphenism.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Changes of body color have important effects for animals in adapting to variable environments. The migratory locust exhibits body color polyphenism between solitary and gregarious individuals, with the former displaying a uniform green coloration and the latter having a prominent pattern of black dorsal and brown ventral surface. However, the molecular mechanism underlying the density-dependent body color changes of conspecific locusts remain largely unknown. Here, we found that upregulation of β-carotene-binding protein promotes the accumulation of red pigment, which added to the green color palette present in solitary locusts changes it from green to black, and that downregulation of this protein led to the reverse, changing the color of gregarious locusts from black to green. Our results provide insight that color changes of locusts are dependent on variation in the red β-carotene pigment binding to βCBP. This finding of animal coloration corresponds with trichromatic theory of color vision.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.