ArticleBMC geriatrics2019
Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort.
Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Cognitive impairment and contexts: examining the intersections of social activity participation and neighborhood perceptions.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Neighbourhood Socioeconomic Processes and Dynamics and Healthy Ageing: A Scoping Review.International journal of environmental research and public health · 2022Article
- Sex and Gender Differences in Environmental Influences on Dementia Incidence in Germany, 2014-2019: An Observational Cohort Study Based on Health Claims Data.Journal of Alzheimer's disease : JAD · 2022Observational
- Effects of Environmental Quality Perception on Depression: Subjective Social Class as a Mediator.International journal of environmental research and public health · 2021Article
- Article
- CCCDTD5: Reducing the risk of later-life dementia. Evidence informing the Fifth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD-5).Alzheimer's & dementia (New York, N. Y.) · 2020Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSocioeconomic level of residential environment was found to influence cognitive performance. However, individuals from the same place of residence may be affected differently. We aim to investigate for the first time the influence of individual activity space on the association between neighborhood socioeconomic status (NSES) and the risk of dementia.
methodsIn the frame of the Three-City cohort, a French population-based study, we followed longitudinally (12 years) 7009 participants aged over 65. The activity space (i.e., the spatial area through which a person moves daily) was defined using two questions from Lawton's Instrumental Activities of Daily Living scale ("Goes shopping independently","Travels alone"), and one question about mobility restriction. The survival analysis was performed using a Cox marginal model that takes into account intra-neighborhood correlations and includes a large number of potential confounders.
resultsAmong people with a limited activity space (n = 772, 11%), risk of dementia is increased in subjects living in a deprived area (characterized by high GINI index or low median income) compared to those living in more favored.
conclusionThis study shows that the individual activity space modifies the association between NSES and the risk of dementia providing a more complete picture of residential inequalities. If confirmed in different populations, these findings suggest that people with limited activity space and living in a deprived neighborhood are particularly at risk and should be targeted for prevention.
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